| 1 |
2024 |
Yuichi Nakahara, Tomoko Kawaguchi, Yutaka Matsuda, Yuta Endo, Masayo Date, Kazutoshi Takahashi, Keisuke Kato, Takahiro Okasora, Daisuke Ejima, Aiichiro Nagaki. Spatiotemporal Control of Protein Refolding through Flash-Change Reaction Conditions, Langmuir. 2024; 40: 8483.
https://doi.org/10.1021/acs.langmuir.4c00024 |
| 2 |
2022 |
Yuichi Nakahara, Brian A. Mendelsohn, Yutaka Matsuda. Antibody–Drug Conjugate Synthesis Using Continuous Flow Microreactor Technology, Organic Process Research & Development. 2022; 26: 2766.
https://doi.org/10.1021/acs.oprd.2c00217 |
| 3 |
2024 |
Shunsuke Yamazaki, Kazutoshi Takahashi, Yutaka Matsuda. Tag-free protein modification by lipoate ligase A: exploring substrate tolerance, Analytical Sciences. 2024; 40: 1111.
https://doi.org/10.1007/s44211-024-00534-6 |
| 4 |
2024 |
Yuichi Nakahara, Yuta Endo, Monica Leung, Brian A. Mendelsohn, Yutaka Matsuda. Implementing an Efficient Technology Transfer for Biomolecule Production: A Case Study on Continuous-Mode Processes, Organic Process Research & Development. 2024; 28: 3950.
https://doi.org/10.1021/acs.oprd.4c00172 |
| 5 |
2023 |
Tomohiro Fujii, Kenichiro Ito, Kazutoshi Takahashi, Tsubasa Aoki, Rika Takasugi, Takuya Seki, Yusuke Iwai, Tomohiro Watanabe, Ryusuke Hirama, Ryo Tsumura, Hirobumi Fuchigami, Masahiro Yasunaga, Yutaka Matsuda. Bispecific Antibodies Produced via Chemical Site-Specific Conjugation Technology: AJICAP Second-Generation, ACS Medicinal Chemistry Letters. 2023; 14: 1767.
https://doi.org/10.1021/acsmedchemlett.3c00414 |
| 6 |
2023 |
Tomohiro Fujii, Yutaka Matsuda. Novel formats of antibody conjugates: recent advances in payload diversity, conjugation, and linker chemistry, Expert Opinion on Biological Therapy. 2023; 23: 1053.
https://doi.org/10.1080/14712598.2023.2276873 |
| 7 |
2024 |
Swapnali Parit, Ajit Manchare, Amol D. Gholap, Prashant Mundhe, Navnath Hatvate, Satish Rojekar, Vandana Patravale. Antibody-Drug Conjugates: A promising breakthrough in cancer therapy, International Journal of Pharmaceutics. 2024; 659: 124211124211.
https://doi.org/10.1016/j.ijpharm.2024.124211 |
| 8 |
2023 |
Tomohiro Fujii, Yutaka Matsuda, Takuya Seki, Natsuki Shikida, Yusuke Iwai, Yuri Ooba, Kazutoshi Takahashi, Muneki Isokawa, Sayaka Kawaguchi, Noriko Hatada, Tomohiro Watanabe, Rika Takasugi, Akira Nakayama, Kazutaka Shimbo, Brian A. Mendelsohn, Tatsuya Okuzumi, Kei Yamada. AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody–Drug Conjugate Production, Bioconjugate Chemistry. 2023; acs.bioconjchem.3c00040.
https://doi.org/10.1021/acs.bioconjchem.3c00040 |
| 9 |
2024 |
Shunsuke Yamazaki, Kenichiro Ito, Tsubasa Aoki, Naoko Arashida, Tomohiro Watanabe, Tomohiro Fujii, Yutaka Matsuda. Biological Evaluation of Antibody-Drug Conjugates Produced by Tag-Free Lipoate Ligase A Modification, Biochemistry. 2024; 63: 644.
https://doi.org/10.1021/acs.biochem.3c00513 |
| 10 |
2022 |
Takuya Seki, Kei Yamada, Yuri Ooba, Tomohiro Fujii, Takahiro Narita, Akira Nakayama, Yoshiro Kitahara, Brian A. Mendelsohn, Yutaka Matsuda, Tatsuya Okuzumi. Biological Evaluation of Maytansinoid-Based Site-Specific Antibody-Drug Conjugate Produced by Fully Chemical Conjugation Approach: AJICAP®, Frontiers in Bioscience-Landmark. 2022; 27: 234.
https://doi.org/10.31083/j.fbl2708234 |
| 11 |
2024 |
Tomohiro Watanabe, Naoko Arashida, Tomohiro Fujii, Natsuki Shikida, Kenichiro Ito, Kazutaka Shimbo, Takuya Seki, Yusuke Iwai, Ryusuke Hirama, Noriko Hatada, Akira Nakayama, Tatsuya Okuzumi, Yutaka Matsuda. Exo-Cleavable Linkers: Enhanced Stability and Therapeutic Efficacy in Antibody–Drug Conjugates, Journal of Medicinal Chemistry. 2024; 67: 18124.
https://doi.org/10.1021/acs.jmedchem.4c01251 |
| 12 |
2023 |
Tomohiro Watanabe, Tomohiro Fujii, Jason T. Stofleth, Rika Takasugi, Kazutoshi Takahashi, Yutaka Matsuda. Scale-Up Synthesis of Site-Specific Antibody–Drug Conjugates Using AJICAP Second-Generation Technology, Organic Process Research & Development. 2023; 27: 1136.
https://doi.org/10.1021/acs.oprd.3c00111 |
