Comparative result showing impact of age on various markers
Variables$
Adolescents (n= 140)
Young adults (n= 140)
Pvalue
Non-obese (n= 70)
Obese (n= 70)
Non-obese (n= 70)
Obese (n= 70)
Adiponectin (μg/mL)
8.7 ± 1.79
7.1 ± 1.79
5.9 ± 1.94
4.1 ± 1.43
*P = 0.01#P = 0.01
hs-CRP (mg/L)
1.9 ± 0.85
1.9 ± 0.83
2.1 ± 0.77
2.2 ± 0.98
*P = 0.04#P = 0.01
C3 (mg/dL)
150.7 ± 30.93
153.5 ± 32.23
156.9 ± 14.68
172.6 ± 17.8
*P = 0.51#P = 0.001
C4 (mg/dL)
30.7 ± 11.41
38.5 ± 15.92
33 ± 8.20
36.3 ± 7.28
*P = 0.68#P = 0.38
Cp (IU/L)
68.2 ± 20.05
72 ± 20.17
78.07 ± 20.12
96.3 ± 16.22
*P = 0.01#P = 0.001
TBARS (nmol/mL)
5.1 ± 0.77
5.1 ± 1.31
4.7 ± 1.31
6.7 ± 0.01
*P = 0.289#P = 0.01
TAC (mmol/L)
1.6 ± 0.56
1.7 ± 0.56
1.6 ± 0.34
0.7 ± 0.48
*P = 1.0#P = 0.01
Results presented as geometric mean ± SD. $ unpaired t test; * non-obese adolescents vs. non-obese young adults; # obese adolescents vs. obese young adults. Intergroup analysis: 2 way analysis of variance (ANOVA)
Declarations
Acknowledgments
The authors thank all participants in the study and the institution without whose support the work would not have been possible. We thank the institution for supporting us with the infrastructure and equipments for the conduct of the study. We also thank the technical staff for providing help with the analysis.
The authors declare that they have no conflict of interest.
Ethical approval
JNMC Institutional Ethics Committee on Human Subjects Research ethical committee clearance was obtained (Ref No: KLEU/D 6596-6599). This study complies with the Declaration of Helsinki.
Consent to participate
Written consent form if aged more than 18 and assent from the participants with consent of the parent or the guardian if aged less than 18.
Consent to publication
The informed consent to publication was obtained from the parent of the patient.
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