Recent developments in 3D printing of BMMs for biomedical applications
3D printing technique | Materials and printed BMMs | Reference(s) |
Tissue engineering | ||
FDM | PLA–scaffolds | [19] |
DIW | Alg/Gel–scaffolds | [22] |
Alg/SF protein–scaffolds | [23] | |
Extrusion | Alg/NC, hyaluronic acid–scaffolds | [24] |
FDM | PCL–scaffolds | [32] |
BJ | 45S5 BG/TCP–scaffolds | [34] |
SLS | 45S5 BG–scaffolds | [35] |
DIW | 45S5 BG–scaffolds | [36] |
BGs/PVA–scaffolds | [37] | |
Cu-doped BG-based composite scaffolds | [38] | |
FDM | BG/PCL–scaffolds | [39] |
BG/PLA–scaffolds | [40] | |
45S5 BG/PHBV–resorbable scaffolds | [41] | |
Ag-doped BG-based ceramic scaffolds | [42] | |
DIW | SF/Gel/BG–bone constructs | [43] |
FDM | PCL/nano-HA–composite scaffolds | [138] |
Drug delivery | ||
BJ | CaP/silica-based nanocomposite implant | [139] |
CaP/TCP/HA/dextrin-based scaffolds | [140] | |
PBF | CaP/PHBV-based nanocomposite scaffolds | [141] |
PAM | Levetiracetam/PVP-vinyl acetate copolymer (PVAc)–tablets | [142] |
Ethylcellulose/HPMC/PVP/cellulose acetate–controlled release shell | [64] | |
FDM | Haloperidol/Kollidon® VA64/Kollicoat® IR/Affinsiol™ 15 cP/HPMC acetate succinate (HPMCAS)–tablet | [143] |
Clotrimazole/TPUs–intravaginal ring | [144] | |
Isoniazid (INZ)/rifampicin (RFC)/hydroxypropyl cellulose (HPC)/hypromellose acetate succinate (HPMC-AS)–bilayer tablet | [145] | |
Semi-solid extrusion | Levetiracetam/HPC–tablets | [146] |
Tacrolimus/Gelucire 44/14/Gelucire 48/16–suppositories | [147] | |
Lamotrigine/Gel/HPMC–drug formulations | [148] | |
SLS | Lopinavir/Kollicoat®/Candurin® NXT Ruby Red–printlets | [149] |
Clindamycin palmitate/microcrystalline cellulose (MCC)/lactose monohydrate (LMH)–tablets | [150] | |
SLA | Lidocaine hydrochloride/Elastic Resin–bladder devices | [151] |
Hydrochlorothiazide/amlodipine/atenolol/irbesartan with PEGDA/diphenyl(2, 4, 6-trimethyl-benzoyl) phosphine oxide (TPO)–antihypertensive polyprintlet | [152] | |
Direct powder extrusion (DPE) | Tramadol/HPC/polyethylene oxide (PEO)–opioid medicines | [153] |
Itraconazole/HPC–UL, SSL, SL, and L (different HPC grades/compositions)–drug products | [154] | |
FDM | PLA/PVA-based mouthguard | [62] |
Surgical and diagnostic tools | ||
SLS | Virgin and recycled Dura-Form EX plastic powder–surgical tool kit | [67] |
FDM | PLA-based Army-Navy surgical retractor | [68] |
PLA-based microchannel system | [75] | |
Graphene/PLA–ring- and disc-shaped electrodes | [76] | |
Graphene-based enzymatic biosensor | [77] | |
Graphene/PLA–electrode | [79] | |
DIW-AJP | Ag–microelectrode arrays | [82] |
SLA | PEGDA–biomicrofluidic devices | [83] |
SLS | Cu nanoparticles/polyethylene-naphthalate (PEN)–flexible touch panel | [86] |
FDM | PLA/PAM/HPMC–hydrogel wound dressings | [69] |
FDM | Thermoplastic–frame for magnetic focus lateral flow sensor detecting cervical cancer biomarkers | [78] |
Implants and prosthetics | ||
DED | Si3N4/Al2O3/HA/Ti6Al4V–composites | [92] |
DIW | Ti/Pluronic F-127–scaffolds | [97] |
SLM | Ti-6Al-4V-based implants | [98] |
SLA | Composites-based dental crowns | [155] |
SLA | Antimicrobial HA-based dental bite | [156] |
DLP | Polymer-based dental crowns and bridges | [157] |
DLP | Zirconia-based dental ceramic prostheses | [158] |
MJ | Biocompatible photopolymer-based interim dental crowns | [159] |
FDM | PEKK-based bone analogs | [117] |
FDM | PMMA/PEEK–cranial implant | [118] |
PMMA–medical implants | [120] | |
PLA–interference screw | [125] | |
DMLS | Ti-6Al-4V–porous channel dental implant | [133] |
FDM | ABS–human skull; PEEK–porous implant | [136] |
FDM | PLA/GS–interference fixation screws | [137] |
The authors acknowledge the financial support provided for this work by the Research Council, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
GAA: Conceptualization, Writing—original draft, Writing—review & editing. SSA and RSD: Writing—original draft, Writing—review & editing. AW: Writing—review & editing.
The authors declare no conflicts of interest.
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This work received support from the University Research Grant [ASP/01/RE/TEC/2022/74] provided by the Research Council, University of Sri Jayewardenepura, Nugegoda, Sri Lanka. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
© The Author(s) 2024.