The main clinical characteristics of the study population (median and quartiles)
Parameter
Patients with ischemic CHF and hypertension (n = 90)
Non-CHF patients with hypertension (n = 50)
Р value
Age, years
63 (59, 68)
58 (52, 63)
0.22
Males, n (%)
46 (51)
30 (60)
0.04
Females, n (%)
44 (49)
20 (40)
0.03
LA ESD, cm
4.2 (3.7, 4.6)
3.7 (3.4, 3.8)
0.01
RA ESD, cm
3.8 (3.6, 4.5)
3.5 (3.3, 3.7)
0.01
LV EDD, cm
5.2 (4.8, 5.5)
4.9 (4.8, 5.1)
0.04
RV EDD, cm
3.0 (2.7, 3.2)
2.7 (2.6, 3.0)
0.01
LVMI, g/m2
103 (83, 128)
88.5 (79.8, 104.5)
0.03
LVEF, %
46 (38, 63)
70 (66, 75)
0.01
Daytime SBP variability, mmHg
17 (15, 20)
16 (14, 19)
0.06
Nighttime SBP variability, mmHg
12 (9, 18)
11 (8, 13)
0.11
Daytime DBP variability, mmHg
12 (10, 13)
12 (10, 14)
0.07
Nighttime DBP variability, mmHg
8 (8, 11)
11.5 (9, 12)
0.09
Daytime SBP hypotensive episodes, %
6 (0, 11)
3 (0, 5)
0.11
Nighttime SBP hypotensive episodes, %
0 (0, 0)
0 (0, 0)
0.06
Daytime DBP hypotensive episodes, %
8 (1, 18)
11 (0.00, 22.75)
0.08
Nighttime DBP hypotensive episodes, %
8 (0, 15)
0 (0, 0)
0.03
Duration CHD, months
60.1 (35.7, 86.1)
-
-
Duration CHF, months
46.2 (20.6, 68.7)
-
-
-: not applicable. Data presented as median with low and upper quartiles
Declarations
Author contributions
NSA: Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing—original draft. YGS: Formal analysis. NDM and TYL: Investigation. ARK: Methodology, Investigation, Resources. LEK: Visualization, Writing—review & editing. OVB: Data curation, Investigation. All authors read and approved the submitted version.
Conflicts of interest
The authors declare that they have no conflicts of interest.
Ethical approval
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The conduct of this study was approved by the Ethics Committee of the Federal State Budgetary Educational Institution of Higher Education V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of the Russian Federation.
Consent to participate
Informed consent to participate in the study was obtained from all participants.
Consent to publication
Not applicable.
Availability of data and materials
The datasets that support the findings of this study are available from the author upon reasonable request. If someone wants to request the data you should contact Oksana V. Bugaeva, bugaeva.ov@staff.sgmu.ru.
Funding
The reported study was funded by the Federal State Budgetary Educational Institution of Higher Education V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of the Russian Federation according to Research Project [SSMU-2021-001]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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