The results of regression analysis of the dependence of the variability of DBP at night on echocardiographic parameters and functional class of CHF
Variable
Standardized coefficients
Non-standardized coefficients
t
P level
Beta
Str.Err.
Beta
Str.Err.
Intercept
-
-
36.17093
6.365803
5.68207
< 0.001
FC of CHF
–0.745443
0.151638
–8.18534
1.665057
–4.91595
< 0.001
RA ESD
–0.459399
0.185459
–3.38723
1.367422
–2.47709
0.027
RV EDD
0.296437
0.189023
3.80125
2.423857
1.56826
0.139
FC: functional class; Str.Err.: standard error; -: not applicable. The multiple correlation coefficient R is 0.84; F test is 11.110, P = 0.005
Declarations
Author contributions
NSA: Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing—original draft. YGS: Formal analysis. NDM and TYL: Investigation. ARK: Methodology, Investigation, Resources. LEK: Visualization, Writing—review & editing. OVB: Data curation, Investigation. All authors read and approved the submitted version.
Conflicts of interest
The authors declare that they have no conflicts of interest.
Ethical approval
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The conduct of this study was approved by the Ethics Committee of the Federal State Budgetary Educational Institution of Higher Education V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of the Russian Federation.
Consent to participate
Informed consent to participate in the study was obtained from all participants.
Consent to publication
Not applicable.
Availability of data and materials
The datasets that support the findings of this study are available from the author upon reasonable request. If someone wants to request the data you should contact Oksana V. Bugaeva, bugaeva.ov@staff.sgmu.ru.
Funding
The reported study was funded by the Federal State Budgetary Educational Institution of Higher Education V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of the Russian Federation according to Research Project [SSMU-2021-001]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Sitnikova MY, Lyasnikova EA, Yurchenko AV, Trukshina MA, Libis RA, Kondratenko VY, et al. Results of Russian hospital chronic heart failure registry in three subjects of Russian Federation.Kardiologiia. 2015;55:5–13. Russian. [DOI] [PubMed]
Shwartz YG, Martynovich TV, Akimova NS, Fedotov EA. The role of genetic factors in the formation of chronic heart failure.J Heart Fail. 2013;14:369–76. Russian.
Martynovich TV, Akimova NS, Fedotov EA, Korsunova EN, Sokolov IM. Analysis of gene polymorphism of the renin-angiotensin-aldosterone system in patients with cardiovascular diseases.Mod Probl Sci Educ. 2015;3. Russian.
McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al.; ESC Scientific Document Group. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). With the special contribution of the Heart Failure Association (HFA) of the ESC.Eur J Heart Fail. 2022;24:4–131. [DOI] [PubMed]
Mills KT, Stefanescu A, He J. The global epidemiology of hypertension.Nat Rev Nephrol. 2020;16:223–37. [DOI] [PubMed] [PMC]
van Riet EE, Hoes AW, Wagenaar KP, Limburg A, Landman MA, Rutten FH. Epidemiology of heart failure: the prevalence of heart failure and ventricular dysfunction in older adults over time. A systematic review.Eur J Heart Fail. 2016;18:242–52. [DOI] [PubMed]
Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, Chang AR, Cheng S, et al.; American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics—2018 update: a report from the American Heart Association.Circulation. 2018;137:e67–492. [DOI] [PubMed]
McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al.; ESC Scientific Document Group. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure.Eur Heart J. 2021;42:3599–726. [DOI] [PubMed]
Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Colvin MM, et al. 2017 ACC/AHA/HFSA focused update of the 2013 ACCF/AHA Guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America.Circulation. 2017;136:e137–61. [DOI] [PubMed]
Fomin IV. Chronic heart failure in the Russian Federation: What do we know and what to do.Russ J Cardiol. 2016;8:7–13. Russian. [DOI]
Sutton GC. Epidemiologic aspects of heart failure.Am Heart J. 1990;120:1538–40. [DOI] [PubMed]
Daibanyrova LV. Chronic heart failure in young patients.Med Sci. 2017;4:38–41. Russian.
Felker GM, Shaw LK, O’Connor CM. A standardized definition of ischemic cardiomyopathy for use in clinical research.J Am Coll Cardiol. 2002;39:210–8. [DOI] [PubMed]
Ostroumova OD, Kochetkov AI, Guseva TF. Variability of arterial pressure in arterial hypertension in combination with ischemic heart disease: prognostic significance and possibilities of correction in real clinical practice.Arterial Hypertens. 2018;24:246–56. Russian.
Cautela J, Tartiere JM, Cohen-Solal A, Bellemain-Appaix A, Theron A, Tibi T, et al. Management of low blood pressure in ambulatory heart failure with reduced ejection fraction patients.Eur J Heart Fail. 2020;22:1357–65. [DOI] [PubMed] [PMC]
Shalygin LD. Modern concepts of blood pressure variability and its clinical significance.Ideas Innov. 2016;1:30–40. Russian.
Parati G, Stergiou GS, Dolan E, Bilo G. Blood pressure variability: clinical relevance and application.J Clin Hypertens (Greenwich). 2018;20:1133–7. [DOI] [PubMed] [PMC]
Russian Society of Cardiology (RSC). 2020 clinical practice guidelines for chronic heart failure.Russ J Cardiology. 2020;25:4083. Russian. [DOI]
Gheorghiade M, Abraham WT, Albert NM, Greenberg BH, O’Connor CM, She L, et al.; OPTIMIZE-HF Investigators and Coordinators. Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure.JAMA. 2006;296:2217–26. [DOI] [PubMed]
Desai RV, Banach M, Ahmed MI, Mujib M, Aban I, Love TE, et al. Impact of baseline systolic blood pressure on long-term outcomes in patients with advanced chronic systolic heart failure (insights from the BEST trial).Am J Cardiol. 2010;106:221–7. [DOI] [PubMed] [PMC]
Banach M, Bhatia V, Feller MA, Mujib M, Desai RV, Ahmed MI, et al. Relation of baseline systolic blood pressure and long-term outcomes in ambulatory patients with chronic mild to moderate heart failure.Am J Cardiol. 2011;107:1208–14. [DOI] [PubMed] [PMC]
Tsimploulis A, Lam PH, Arundel C, Singh SN, Morgan CJ, Faselis C, et al. Systolic blood pressure and outcomes in patients with heart failure with preserved ejection fraction.JAMA Cardiol. 2018;3:288–97. [DOI] [PubMed] [PMC]
Vidal-Petiot E, Ford I, Greenlaw N, Ferrari R, Fox KM, Tardif JC, et al.; CLARIFY Investigators. Cardiovascular event rates and mortality according to achieved systolic and diastolic blood pressure in patients with stable coronary artery disease: an international cohort study.Lancet. 2016;388:2142–52. [DOI] [PubMed]
Tsujimoto T. Low diastolic blood pressure for HFpEF.Int J Cardiol. 2018;270:190. [DOI] [PubMed]
Lee DS, Ghosh N, Floras JS, Newton GE, Austin PC, Wang X, et al. Association of blood pressure at hospital discharge with mortality in patients diagnosed with heart failure.Circ Heart Fail. 2009;2:616–23. [DOI] [PubMed]
Serov VA, Shutov AM, Serova DV, Shmel’kova EIu, Shevchenko SV. Prognostic value of detection of arterial hypotensive episodes in patients with chronic heart failure.Ter Arkh. 2014;86:8–12. Russian. [PubMed]
Gorelik O, Feldman L, Cohen N. Heart failure and orthostatic hypotension.Heart Fail Rev. 2016;21:529–38. [DOI] [PubMed]
Juraschek SP, Appel LJ, Miller ER 3rd, Mukamal KJ, Lipsitz LA. Hypertension treatment effects on orthostatic hypotension and its relationship with cardiovascular disease.Hypertension. 2018;72:986–93. [DOI] [PubMed] [PMC]
Russian Society of Cardiology (RSC). 2020 clinical practice guidelines for stable coronary artery disease.Russ J Cardiology. 2020;25:4076. Russian. [DOI]
Russian Society of Cardiology (RSC). Arterial hypertension in adults. Clinical guidelines 2020.Russ J Cardiology. 2020;25:3786. Russian. [DOI]
World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects.JAMA. 2013;310:2191–4. [DOI] [PubMed] [PMC]
Dregan A, Ravindrarajah R, Hazra N, Hamada S, Jackson SH, Gulliford MC. Longitudinal trends in hypertension management and mortality among octogenarians: prospective cohort study.Hypertension. 2016;68:97–105. [DOI] [PubMed] [PMC]
Denardo SJ, Gong Y, Nichols WW, Messerli FH, Bavry AA, Cooper-Dehoff RM, et al. Blood pressure and outcomes in very old hypertensive coronary artery disease patients: an INVEST substudy.Am J Med. 2010;123:719–26. [DOI] [PubMed] [PMC]
Bangalore S, Qin J, Sloan S, Murphy SA, Cannon CP; PROVE IT-TIMI 22 Trial Investigators. What is the optimal blood pressure in patients after acute coronary syndromes? Relationship of blood pressure and cardiovascular events in the PRavastatin OR atorVastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction (PROVE IT-TIMI) 22 trial.Circulation. 2010;122:2142–51. [DOI] [PubMed]
Protogerou AD, Safar ME, Iaria P, Safar H, Le Dudal K, Filipovsky J, et al. Diastolic blood pressure and mortality in the elderly with cardiovascular disease.Hypertension. 2007;50:172–80. [DOI] [PubMed]
Divisón-Garrote JA, Ruilope LM, de la Sierra A, de la Cruz JJ, Vinyoles E, Gorostidi M, et al. Magnitude of hypotension based on office and ambulatory blood pressure monitoring: results from a cohort of 5066 treated hypertensive patients aged 80 years and older.J Am Med Dir Assoc. 2017;18:452.e1–6. [DOI] [PubMed]
Sharashova EE, Kholmatova KK, Gorbatova MA, Grjibovski AM. Application of the multivariable linear regression analysis in healthcare using SPSS software.Sci Healthcare. 2017;3:5–31. Russian.
Drapkina OM, Kaburova AN. Vascular stiffness and diastolic heart failure.Ter Arkh. 2013;85:75–81. Russian. [PubMed]
Drapkina OM, Dadaeva VA. Vascular wall stiffness in chronic heart failure.Clinician. 2013:27–30. Russian.