TGFBR2 (rs764522) gene polymorphic genotypes among different types of CHD cases compared to controls
TGFBR2 (rs764522) genotype
Controls
VSD
ASD
TOF
Total
C/C
40
6
4
4
54
40.0%
14.0%
19.0%
36.4%
30.9%
G/G
0
9
5
2
16
0.0%
20.9%
23.8%
18.2%
9.1%
C/G
60
28
12
5
105
60.0%
65.1%
57.1%
45.5%
60.0%
Fisher’s exact test – P-value
34.143 – P < 0.0001*
*: P-value significant < 0.05
Declarations
Author contributions
ND: Formal analysis, Investigation, Writing—original draft. ESS and AAHE: Formal analysis, Investigation, Writing—original draft, Writing—review & editing. FRA, IE, and RE: Conceptualization, Writing—original draft, Writing—review & editing. All authors read and approved the submitted version.
Conflicts of interest
All authors declare that they have no conflicts of interest.
Ethical approval
The Ethical Committee at the Faculty of Medicine, Menoufia University approved the study (No. 11.2/2020 INTM2). The study is in accordance with the ethical standards of institutional research committee and with the 1964 Helsinki Declaration and its later amendments.
Consent to participate
An informed consent was obtained from the parents of all participating subjects of this study.
Consent to publication
Not applicable.
Availability of data and materials
The datasets that support the findings of this study are available from the corresponding author upon reasonable request.
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