Binary logistic regression between each SNP and the incidence of CHD
Variable
B
Chi-square
P-value
OR
95% CI
Lower
Upper
Sex
0.423
1.332
0.248
1.526
0.745
3.127
rs6785358 (total)
8.528
0.014
rs6785358 (AA)
–0.022
0.003
0.955
0.979
0.460
2.083
rs6785358 (GG)
1.836
7.802
0.005
6.272
1.729
22.747
rs764522 (total)
4.951
0.084
rs764522 (CC)
–0.934
4.951
0.026
0.393
0.172
0.895
rs764522 (GG)
21.342
0.000
0.998
0.000
Constant
–0.718
3.294
0.070
0.488
B: binary logistic regression coefficient. Blank cells represent “not detected”. rs6785358 (AG), rs764522 (CG) are used as reference for each related SNP
Declarations
Author contributions
ND: Formal analysis, Investigation, Writing—original draft. ESS and AAHE: Formal analysis, Investigation, Writing—original draft, Writing—review & editing. FRA, IE, and RE: Conceptualization, Writing—original draft, Writing—review & editing. All authors read and approved the submitted version.
Conflicts of interest
All authors declare that they have no conflicts of interest.
Ethical approval
The Ethical Committee at the Faculty of Medicine, Menoufia University approved the study (No. 11.2/2020 INTM2). The study is in accordance with the ethical standards of institutional research committee and with the 1964 Helsinki Declaration and its later amendments.
Consent to participate
An informed consent was obtained from the parents of all participating subjects of this study.
Consent to publication
Not applicable.
Availability of data and materials
The datasets that support the findings of this study are available from the corresponding author upon reasonable request.
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