aMMP-8 GCF mean values and clinical parameters of tooth for the different groups, before and after treatment

VariableTime-pointHealthy (H)Gingivitis (G)Periodontitis (P)Multiple comparisons
aMMP-8 (ng/mL)T0
T3
9.62 ± 4.30
8.99 ± 5.10
13.98 ± 4.70
11.08 ± 3.90
21.82 ± 5.80
15.03 ± 4.10
H vs. G*
H vs. P*
G vs. P*
GIT0
T3
0.48 ± 0.03
0.42 ± 0.05
2.44 ± 0.42
1.12 ± 0.35
(T0 vs. T3*)
2.83 ± 0.89
2.04 ± 0.67
(T0 vs. T3*)
H vs. G*
H vs. P*
G vs. P
PIT0
T3
0.65 ± 0.39
0.32 ± 0.23
1.82 ± 0.82
1.13 ± 0.76
(T0 vs. T3*)
2.66 ± 0.71
1.83 ± 0.45
(T0 vs. T3*)
H vs. G*
H vs. P*
G vs. P*
BOPIT0
T3
0.00
0.00
1.94 ± 0.87
0.93 ± 0.36
(T0 vs. T3*)
2.57 ± 0.58
1.13 ± 0.68
H vs. G*
H vs. P*
G vs. P
PD (mm)T0
T3
1.55 ± 0.33
1.52 ± 0.35
2.93 ± 0.63
1.91 ± 0.78
(T0 vs. T3*)
4.58 ± 0.74
2.89 ± 0.86
H vs. G*
H vs. P*
G vs. P*
rBL (mm)T0
T3
2.30 ± 0.51
2.20 ± 0.33
3.00 ± 0.42
2.80 ± 0.28
6.40 ± 0.19
5.10 ± 0.55
H vs. G
H vs. P*
G vs. P*

Values are presented as mean ± SD. *: P ≤ 0.05