Table Info

Table 2.

Summary of regions that were aggregated to create four metrics for each patient of the cognitively impaired cohort

	MIMneuro^®	CereMetrix^®
Frontal lobe	Frontal lobe	Anterior orbital gyrus Gyrus rectus Inferior frontal gyrus, pars opercularis Inferior frontal gyrus, pars orbitalis Inferior frontal gyrus, pars triangularis Lateral orbital gyrus Medial orbital gyrus Medial orbitofrontal cortex Middle frontal gyrus Olfactory cortex Posterior orbital gyrus Precentral gyrus Superior frontal gyrus Superior frontal gyrus, medial part Supplementary motor area
Parietal lobe	Parietal lobe	Angular gyrus Inferior parietal lobule Postcentral gyrus Precuneus Superior parietal lobule Supramarginal gyrus
Temporal lobe	Temporal lobe	Fusiform gyrus Heschl’s gyrus Inferior temporal gyrus Middle temporal gyrus Middle temporal pole Superior temporal gyrus Superior temporal pole
Internal structures	Amygdala Caudate Cingulate gyrus Globus pallidus Hippocampus Parahippocampal gyrus Putamen Thalamus	Amygdala Anterior cingulate gyrus Caudate Globus pallidus Hippocampus Middle cingulate gyrus Parahippocampal gyrus Posterior cingulate gyrus Putamen Thalamus

Supplementary materials

The supplementary materials for this article are available at:

https://www.explorationpub.com/uploads/Article/file/100122_sup_1.pdf.

Declarations

Acknowledgments

We would like to thank CereHealth Corp. for their donation of patient data and support of this study, and individuals Shane Quint, Laurie Haynie, Michaela Olson, Logan Langholz, and Christine Salva for their contributions to this work.

Author contributions

LMQ contributed to the conception and design of the study. CAR also contributed to its design. With some assistance from acknowledged individuals, LMQ processed all clinical and imaging data for the template and the cognitively impaired cohort. LMQ generated the template and performed all testing and statistical analysis. CAR performed all visual reads on the cognitively impaired cohort. LMQ wrote the first draft of the manuscript. CAR wrote sections of the manuscript. All authors contributed to manuscript revision, read, and approved the submitted version.

Conflicts of interest

Lindsay Quandt is an employee of CereHealth Corporation, the parent company of CereScan and CereMetrix Corporations. Cyrus Raji is an independent contractor for CereHealth Corporation.

Ethical approval

This study was approved by the IntegReview Institutional Review Board, Certificate CHDB112019.

Consent to participate

The informed consent to participate in the study was obtained from all participants.

Consent to publication

Not applicable.

Availability of data and materials

The datasets generated and analyzed for this manuscript are not publicly available because they are proprietary resources of CereHealth Corporation. Requests for access should be directed to Lindsay M. Quandt (LQuandt@ceremetrix.io).

Funding

Not applicable.

Copyright

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