Criteria for inclusion and exclusion were used to select patients who participated in this study
Inclusion criteria
Exclusion criteria
A compensated form of a systemic disease, in its remission stage, no more than ten years.
Decompensated form of a systemic disease, patients with Crohn’s disease, more than ten years in combination with another systemic illness.
Patients who use pharmacotherapy as a treatment method for systemic illnesses.
Patients after surgical interventions of systemic pathology.
The patients’ ages range from 18 to 60 years.
The patients’ ages are over 60 years.
Patients with systemic diseases and the presence of teeth.
Patients with systemic diseases and loss of teeth.
Declarations
Acknowledgments
The authors are grateful to Professor Orest Kochan for his advice and support and to Tetiana Yakushevych for professional support in language editing. The work is prepared within an inter-department research project «Development and implementation of differentiated approaches of diagnosis, treatment and prevention of periodontal and oral mucosa diseases» (state registration number 0123U100071).
Author contributions
OD: Conceptualization, Writing—original draft, Writing—review & editing. SC: Conceptualization, Investigation, Writing—review & editing. SB: Investigation, Data curation, Writing—review & editing. NC and ML: Validation, Writing—review & editing, Supervision. LP and KP: Investigation, Data curation, Formal analysis, Writing—review & editing. NM: Conceptualization, Investigation, Writing—original draft. MZ: Writing—review & editing, Supervision. NT: Investigation, Writing—original draft, Writing—review & editing. All authors read and approved the submitted version.
Conflicts of interest
The authors declare that they have no conflicts of interest.
Ethical approval
The Bioethics Committee of I. Horbachevsky Ternopil National Medical University approved the study protocol (excerpt from protocol No. 73) on April 3, 2023. All the patient investigations conformed to the principles outlined in the Council of Europe Convention on Human Rights and Biomedicine (April 4, 1997), the World Health Association Helsinki Declaration on Ethical Principles for Scientific Research with Human Participation (1964–2000), and the Order of the Ministry of Health of Ukraine No. 281 of November 1, 2000; Declaration of Helsinki “World Medical Association Declaration of Helsinki Ethical Principles for Medical Research Involving Human Subjects” (2001), Code of Scientist of Ukraine (2009). All patients’ examinations were done with informed consent.
Consent to participate
Informed consent to participate in the study was obtained from all participants.
Consent to publication
Not applicable.
Availability of data and materials
The datasets for this study will be available on reasonable request to the corresponding author.
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