Clinical characteristics in male and female groups

CharacteristicsMale (N = 1,016)Female (N = 1,640)P value
Age (year)62.00 ± 10.1160.69 ± 9.000.001
Diabetes mellitus (%)24.6121.520.062
Coronary artery disease (%)22.2414.57< 0.001
Hypertension (%)53.6446.59< 0.001
Smoking (%)39.672.50< 0.001
Stroke (%)16.449.02< 0.001
Calcium channel blocker (%)25.0020.550.008
Angiotensin-converting enzyme inhibitors (%)5.123.230.015
Angiotensin II receptor blocker (%)14.4714.700.877
Beta blockers (%)12.708.840.001
Glycosidase inhibitors (%)8.669.090.766
Metformin (%)8.567.990.596
Sulfonylureas (%)4.433.480.213
Insulin (%)3.253.110.841
Statins (%)25.9823.230.106
Waist circumference (cm)89.38 ± 8.4182.45 ± 9.06< 0.001
Hip circumference (cm)98.35 ± 6.6496.14 ± 7.79< 0.001
BMI (kg/m2)25.46 ± 3.2625.10 ± 5.830.042
CAVI8.68 ± 1.418.38 ± 1.24< 0.001
SBP (mmHg)135.91 ± 16.97133.46 ± 17.81< 0.001
DBP (mmHg)85.43 ± 12.7082.27 ± 12.93< 0.001
Creatinine (μmol/L)78.37 ± 19.7460.67 ± 23.00< 0.001
FPG (mmol/L)6.26 ± 1.916.05 ± 2.05< 0.001
UA (μmol/L)363.76 ± 141.42306.02 ± 150.21< 0.001
TC (mmol/L)4.77 ± 1.135.31 ± 1.12< 0.001
HDL-C (mmol/L)1.21 ± 0.301.41 ± 0.42< 0.001
LDL-C (mmol/L)2.72 ± 0.843.00 ± 0.89< 0.001
TG/HDL-C ratio1.66 ± 1.931.47 ± 4.51< 0.001
hs-CRP (mg/L)2.79 ± 6.472.46 ± 5.380.091
Homocysteine (μmol/L)15.50 ± 8.7111.02 ± 4.77< 0.001
HbA1c (%)5.98 ± 1.225.84 ± 1.090.005
TG (mmol/L)1.79 ± 1.511.86 ± 6.450.569

Comparisons between the two groups were analyzed by t-test, and the Wilcoxon-Mann-Whitney test was used for non-normally distributed data (hs-CRP, TG/HDL-C ratio, TG). Proportions were analyzed by χ2-test. BMI: body mass index; CAVI: cardio-ankle vascular index; DBP: diastolic blood pressure; FPG: fasting plasma glucose; HDL-C: high-density lipoprotein cholesterol; hs-CRP: hypersensitive C-reactive protein; LDL-C: low-density lipoprotein cholesterol; SBP: systolic blood pressure; TC: total cholesterol; TG: triglycerides; UA: uric acid