Associations of serum uric acid levels with ocular conditions
| Authors | Years | Title | Results |
|---|---|---|---|
| Xiong et al. [18] | 2023 | Influence of Serum Uric Acid on Macular Choroidal Thickness and Ganglion Cell Inner Plexiform Layer Thickness | Higher uric acid levels are independently associated with macular choroid and ganglion cell inner plexiform layer thinning |
| Wei et al. [19] | 2023 | Serum Uric Acid Levels Are Associated With Macula Microvasculature Changes In Hypertensive White Matter Hyperintensity Patients | Serum uric acid levels are associated with macula microvascular changes in white matter hyperintensity |
| Geng et al. [20] | 2023 | Sex-specific association of serum uric acid trajectories with risk of incident retinal arteriosclerosis in Chinese population: A population-based longitudinal study | Higher serum uric acid levels are significantly associated with an increased risk of incident retinal arteriosclerosis |
| Qin et al. [13] | 2022 | Elevated level of uric acid, but not glucose, in aqueous humor as a risk factor for diabetic macular edema in patients with type 2 diabetes | Increased aqueous humor uric acid is an independent risk factor for diabetic macular edema, and intravitreal uric acid-lowering therapy could be beneficial |
| Yang et al. [21] | 2022 | Association of Serum Uric Acid With Retinal Capillary Plexus | Higher serum uric acid levels are significantly associated with lower vessel density in the retinal capillary plexus |
| Serra et al. [22] | 2021 | Detection of serum uric acid in primary open angle glaucoma: A pilot study | Serum uric acid levels may be decreased and correlated with worsening visual field and optical coherence tomography parameters |
| Li et al. [23] | 2019 | Association of serum uric acid levels with primary open-angle glaucoma: a 5-year case–control study | Decreased uric acid levels may be associated with an increased risk of primary open-angle glaucoma |
| Thounaojam et al. [16] | 2019 | Monosodium Urate Contributes to Retinal Inflammation and Progression of Diabetic Retinopathy | Uric acid contributes to leukostasis in the diabetic retina. Limiting uric acid production and accumulation in the diabetic retina may halt retinal inflammation and prevent hyperglycemia-induced breakdown of the blood-retinal barrier |
| Chen et al. [24] | 2017 | Serum uric acid concentration is associated with hypertensive retinopathy in hypertensive chinese adults | Serum uric acid concentration is significantly associated with hypertensive retinopathy |
This table summarizes various studies that explore the influence of serum uric acid levels on different ocular conditions and retinal changes. The studies listed provide insights into how elevated or decreased serum uric acid levels impact macular choroidal thickness, ganglion cell inner plexiform layer thickness, macula microvasculature, retinal arteriosclerosis, diabetic macular edema, retinal capillary plexus vessel density, primary open-angle glaucoma, diabetic retinopathy, and hypertensive retinopathy
