Data on positive or negative results of articles about the purpose of studies where mesenchymal cells were applied
| Purpose of study | Concrete results | Evasive results |
|---|---|---|
| Role of cells | 0 article | Xie Z et al. 2021 [1]—Promising preclinical and clinical results on the tissue-directed engineering solution in clinical cases. |
| Mechanism of action | Zhang S et al. 2020 [17]—The produced exosomes promote migration, proliferation, and odontogenic differentiation. | 0 article |
| Field of application | Hernandez-Monjaraz B et al. 2020 [13]—Periodontal diseases are cured with clinical success by application to pulpal mesenchymal cells, as these reduce the effect of superoxide dismutase and IL-1 beta. | Yamada Y et al. 2020 [34]—Pulpal mesenchymal cells are used for bone regeneration, periodontitis, and regeneration of the pulp itself. |
| Li Y et al. 2019 [23]—Mesenchymal cells from inflamed pulps regenerate bone and repair periodontal defects, confirmed 3 months post-surgery. | 0 article | |
| Hernandez-Monjaraz B et al. 2018 [37]—Increase bone density and reduce periodontal pocket depth, promising for periodontal disease treatment. | 0 article | |
| Adding cellular effect | Adamička M et al. 2021 [9]—Non-steroidal anti-inflammatories and paracetamol increase the osgteogenic and chondrogenic effects of pulpal mesenchymal cells. | Divya TC et al. 2021 [36]—Aspirin modulates the differentiating effect of pulp mesenchymal cells. |
| Pupo YM et al. 2021 [21]—Collagen-hydroxyapatite networks increase stability, migrate proliferation of pulpal mesenchymal cells. | 0 article | |
| Yuan M et al. 2018 [22]—Aspirin increases the osteogenic effect. | 0 article | |
| Fageeh HN et al. 2021 [30]—The present periodontitis reduces the migratory, healing effect but not the osteogenic effect of pulpal mesenchymal cells. | 0 article | |
| Barbosa RM et al. 2023 [44]—Chitosan, xanthan, and hydroxyapatite membranes in proportion 1:1:2 increase the balance of mechanical and biological properties of pulpal mesenchymal cells. | 0 article | |
| Total | 0/1/3/5 | 1/0/1/1 |
