Table Info

Table 2.

Mann-Whitney U test comparison between the mTBI and control groups on the BrainCheck Battery assessment metrics, with Benjamini-Hochberg adjusted P-values.

Assessment	Metrics	Adjusted P-value	Explanation
Coordination	balance_mean_distance_from_center	< 0.001*	Mean radial distance from center circle
	balance_percent_in_target_mean	< 0.001*	Mean of percentage time in circle
	balance_position	< 0.001*	Mean position from the circle center
	balance_total_duration_in_circle	< 0.001*	Total duration time in circle
	balance_total_duration_out_circle	< 0.001*	Total duration time out of circle
	balance_total_duration_unpressed	0.95	Total duration time not pressing the screen
	balance_total_number_exits	0.80	Total number of times existing the circle
Digit Symbol Substitution	digit_symbol_correct_per_second_mean	0.80	Mean of correct responses in a second
Digit Symbol Substitution	digit_symbol_duration	0.10	Total time taken to complete assessment. Time starts after digit display and ends when correct answer is completed
Flanker	flanker_correct_mean	0.28	Mean of correct responses
	flanker_reaction_time_central_mean	0.87	Mean reaction time of all correct responses in central cue trials
	flanker_reaction_time_congruent_mean	0.51	Mean of all reaction times when arrows point in same direction
	flanker_reaction_time_correct_mean	0.87	Mean reaction time of all correct responses
	flanker_reaction_time_correct_median	0.93	Median reaction time of all correct responses
	flanker_reaction_time_incongruent_mean	0.95	Mean of all reaction times when arrows point in opposite directions
	flanker_reaction_time_incorrect_mean	0.28	Mean reaction time of all incorrect responses
	flanker_reaction_time_spatial_mean	0.83	Mean reaction time of all correct responses in spatial cue trials
Immediate and Delayed Recognition	delayed_recognition_correct	< 0.001*	Number of correct responses
Immediate and Delayed Recognition	immediate_recognition_correct	< 0.001*	Number of correct responses
Stroop	stroop_basic_reaction_time_mean	0.91	Mean reaction time for neutral words
	stroop_basic_reaction_time_median	0.87	Median reaction time for neutral words
	stroop_effect_ms_mean	< 0.001*	Mean reaction time incongruent - congruent (in ms)
	stroop_effect_ratio	< 0.001*	Median reaction time of incongruent / median reaction time of congruent
	stroop_reaction_time_congruent_mean	0.006*	Mean reaction time for all correct answers in congruent trials
	stroop_reaction_time_incongruent_median	0.057	Mean reaction time for all correct answers in incongruent trials
Trail Making	trails_b_duration_median	0.98	Median of response times between each click for TrailMaking B
	trails_b_duration_mean	0.80	Mean of all response times between clicks for Trail Making B
	trails_a_duration_mean	0.87	Mean of all response times between clicks for Trail Making A

Statistically significant P-values

Declarations

Author contributions

DME and YK contributed conception and design of the study; Data acquisition was performed by BF; SY and BH performed the statistical analysis, under the supervision of RHG. SY, BK and HQP wrote the first draft of manuscript, which was revised and approved by BH and RHG. SY, BK, HQP, KS and BH revised the manuscript for submission. All authors read and approved the final manuscript.

Conflicts of interest

The following authors declare the following competing interests: SY, BF, YK, BH, KS, RHG reports personal fees from BrainCheck, outside the submitted work; DME, BF, YK, BH, RHG reports receiving stock options from BrainCheck.

Ethical approval

This study protocol was reviewed and approved by the Baylor College of Medicine IRB.

Consent to participate

Voluntary written informed consent to participate in the study was obtained from all participants.

Consent to publication

Not applicable.

Availability of data and materials

Data may be made available by contacting the corresponding author and with a data use agreement.

Funding

BrainCheck, Inc, provided support in the form of salaries for authors SY, BF, YK, BH, KS, RHG but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript, and only provided financial support in the form of some of the authors’ salaries and research materials (the software battery of tests).

Copyright

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