Clinical characteristics of patients
Parameters | Values (ntotal = 122) |
---|---|
Age, year | 14.0 [11.0; 16.0] |
z Height | 0.42 [–0.25; 1.16] |
z BMI | 0.24 ± 1.04 |
z FVC | 1.11 ± 1.31 |
z FEV1 | 0.31 ± 1.23 |
z FEV1/FVC | –1.01 ± 1.26 |
Change of FEV1 in tests with bronchodilator, n = 50 | 1.12 ± 0.11 |
PNIF, L/min | 44.64 ± 13.49 |
PNIF/FVC | 11.05 [7.89; 14.40] |
Eosinophils, 109/L | 0.28 [0.14; 0.50] |
IgE, ME/mL | 180.01 [81.55; 384.01] |
SNOT-22, scores | 16.0 [10.0; 24.0] |
Postnasal discharge, scores | 1.0 [0.0; 2.0] |
Cough, scores | 2.0 [1.0; 2.0] |
Cough, scores | |
0: no | 23.8% (29/122) |
1–2: low intensity | 59.0% (72/122) |
3–4: medium intensity | 17.2% (21/122) |
z BMI: z-score body mass index; z Height: z-score height; PNIF: peak nasal inspiratory flow; FVC: forced vital capacity of the lungs; FEV1: forced expiratory volume in the first second; SNOT-22: Sinonasal Outcome Test-22; IgE: immunoglobulin E. The data is presented in the form of Me [Q1; Q3], where Me is the median, [Q1; Q3] is 1st and 3rd quartiles in the case of an abnormal distribution of quantities, and in the form of M ± σ, where M is the mean value, σ is the standard deviation in the case of their normal distribution
RNK: Conceptualization, Resources, Investigation, Methodology, Writing—original draft, Writing—review & editing. SVK: Conceptualization, Resources, Investigation, Methodology, Validation, Visualization, Writing—original draft, Writing—review & editing. ASK: Data curation, Resources, Software, Writing—original draft. KVG: Data curation, Investigation, Methodology, Writing—original draft. DYO: Conceptualization, Methodology, Writing—review & editing. AAK: Data curation, Resources, Software, Writing—original draft. AAS: Data curation, Software. GSI: Data curation, Software, Writing—review & editing. MAK: Data curation, Software, Validation, Writing—original draft. NIK: Writing—review & editing. OVK: Resources, Writing—review & editing. VVN: Writing—review & editing. VAB: Methodology, Writing—review & editing. NAG: Methodology, Writing—review & editing. TIE: Conceptualization, Investigation, Formal analysis, Supervision, Resources, Writing—original draft, Writing—review & editing.
The authors declare that they have no conflicts of interest.
The study was performed in accordance with the Helsinki Declaration (2013) and approved by the Ethics Committee of the Volga Region Research Medical University (Protocol No. 13 dated 10.10.2016).
All participants and all primary caregivers provided written informed consent.
Not applicable.
The data used to support the findings of this study are available from the corresponding author upon request (Nailya I. Kubysheva, aibolit70@mail.ru).
Not applicable.
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