Table Info

Table 3.

Comparison between the differential genes related with axonal transport and autophagy across the three stages analyzed (Younger, Elder, and MCI Groups)

Functionality	Younger	Elder	MCI
RAS-associated binding proteins (RABs)	RAB2B, RAB18, RABGAP1L, RAB40B, RAB39A, RAB33A	RAB3C, RAB4A, RAB3GAP1, RAB8B, RAB11FIP2, RAB14, RAB26	RAB3GAP1, RAB3IP, RAB3I, RAB4B, RAB6A, RAB11FIP5, RAB27A, RAB27B, RAB31, RAB34
Kinesin motor proteins (anterograde transport)	KIF1C, KIF9	KIF1A, KIF15, KIF21B	KIF2A, KIF3C, KIF5B, KIF22
Dynein motor proteins (retrograde transport)	DYNC1I2	DYNC1LI1, DYNCC1I1
Autophagy-related cysteine peptidases (ATGs)		ATG2B, ATG4C, ATG13	ATG3, ATG10

Supplementary materials

The supplementary figures for this article are available at: https://www.explorationpub.com/uploads/Article/file/1001299_sup_1.pdf. The supplementary tables for this article are available at: https://www.explorationpub.com/uploads/Article/file/1001299_sup_2.xlsx.

Declarations

Acknowledgments

The author extends gratitude to Dr. Catalina A. Feledi for her valuable discussions and expert assistance in refining idiomatic expressions.

Author contributions

DVG: Conceptualization, Investigation, Visualization, Writing—original draft, Writing—review & editing.

Conflicts of interest

The author declares that he has no conflicts of interest.

Ethical approval

Not required.

Consent to participate

Not required.

Consent to publication

Not required.

Availability of data and materials

The original microarray data corresponding to the patients were gathered by Berchtold et al. [28, 29], and can be accessed under code GSE11882 in GEO database (https://www.ncbi.nlm.nih.gov/geo). The data generated in this study are available from Supplementary materials associated to the present article.

Funding

Not applicable.

Copyright

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