Summary of findings about the role of sex hormones in the risk of NAFLD

Sex hormones, metabolism, and the risk of developing NAFLD
• In the male the risk of NAFLD is higher than women
• In the male low androgens levels may increase the risk of NAFLD
• In the male with obesity/MetS, low androgens levels are frequently observed and are associated with the presence of NAFLD
• In the female with obesity/MetS, the presence of PCOS may increase the risk of NAFLD
• In the female, during the pre-menopausal period, the risk of NAFLD is lesser than men
• In the female, during the post-menopausal period, the risk of NAFLD is similar to men
• Both men with low androgen levels and women with PCOS should be screened for NAFLD