AOS in obesity and IR in animal model studies
Animal tissue/cell type | Components of AOS defense | Effect of obesity/IR | Ref |
---|---|---|---|
3T3-L1 adipocytes of mice | EC-SOD expression | Increased | [75] |
Perirenal, epididymal, and brown adipose tissues of male Wistar rats | SOD, CAT, GPx activities | Decreased | [82] |
Liver of male C57BL/6 mice | Mn-SOD protein level | Decreased | [29] |
Heart of male C57BL/6J mice | CAT protein level/CAT activity | Increased | [76] |
Visceral adipose tissue of female Wistar rats | Mn-SOD, GPx protein levels/Cu/Zn-SOD, GR protein levels | Decreased/unchanged | [81] |
Primary hepatocytes of male C57BL/6J mice | GSH content, GPx, and GR activities | Decreased | [31] |
Soleus muscle of Wistar male rats | Total GSH level/Mn-SOD, CAT, GPx expression | Decreased/unchanged | [77] |
Plasma samples and heart of male fa/fa ZR | SOD/GPx activities | Decreased/unchanged | [30] |
Serum of male Albino rats | MDA level/GSH level | Increased/decreased | [83] |
White adipose tissue of female Wistar rats | SOD1 and GR protein levels | Increased | [78] |
Ref: reference
AP and JS wrote the manuscript and contributed conception. ERI and ESM designed, wrote, and supervised the manuscript. All authors contributed to manuscript revision, read and approved the submitted version.
The authors declare that they have no conflicts of interest.
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This work was funded by the Ministry of Education, Science and Technological Development of the Republic of Serbia (Contract No#451–03–9/2021–14/200017). The funder had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.
© The Author(s) 2022.