Table Info

Table 2.

AOS in obesity and IR in human studies

Human tissue/cell type	Components of AOS defense	Effect of obesity/IR	Ref
Serum of obese women	GPx activity	Decreased	[85]
Plasma of obese children of both sexes	Zn concentration	Decreased	[93]
Serum of morbidly obese male and female patients	Vitamins A, B6, C, D, E concentrations	Decreased	[95]
Serum of obese adolescents	Se concentration	Decreased	[92]
Erythrocytes of obese women	Cu/Zn-SOD, CAT, GPx activities	Decreased	[86]
Serum of male and female T2DM patients	GSH content/GPx, GR activities	Decreased	[32]
Adipose tissue of obese and/or T2DM male and female patients	Mn-SOD, GPx activities	Decreased	[87]
Serum and liver of male and female NAFLD patients	GSH level	Decreased	[33]
Peripheral blood mononuclear cells of obese children of both sexes	Mn-SOD, CAT expression	Decreased	[34]
Serum of MS male and female patients	Vitamin E concentration	Decreased	[96]
Blood samples of obese and overweight children	SOD activity/GSH/GSSG ratio, CAT activity	Increased/decreased (in obese); all decreased (in overweight)	[88]
Blood samples of MS male and female patients	Vitamin C, GSH levels	Decreased	[89]

NAFLD: non-alcoholic fatty liver disease

Declarations

Author contributions

AP and JS wrote the manuscript and contributed conception. ERI and ESM designed, wrote, and supervised the manuscript. All authors contributed to manuscript revision, read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

This work was funded by the Ministry of Education, Science and Technological Development of the Republic of Serbia (Contract No#451–03–9/2021–14/200017). The funder had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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