Correlations between the infrared-AI software test results and patient characteristics
Clinical variables
Value
Infrared-AI software result# (error)
Infrared-AI software result# (hit)
χ2
P value
FP
FN
Total
TP
TN
Total
BMI (kg/m2, n = 349)
Underweight
0
0
0
0
2
2
1.81
0.697*
Normal
16
0
16
7
44
51
Overweight
37
1
38
15
109
124
Obesity
33
1
34
15
69
84
Breast pain
No
74
0
74
17
184
201
1.97
0.16
Yes
12
2
14
20
40
60
Activities and conditions that affect body temperature
No
27
0
27
17
48
65
1.13
0.287
Yes
59
2
61
20
176
196
Breast density
A
7
0
7
5
14
19
7.67
0.081*
B
65
2
67
21
168
189
C
12
0
12
11
42
53
D
2
0
2
0
0
0
BC grade (n = 39)
I
-
0
-
1
-
-
0.39
0.811*
II
1
19
III
1
13
N/A
0
4
Tumor size
T1
-
0
-
19
-
-
6.02
0.120*
T2
1
15
T3
1
2
T4
0
1
Error is the false-positive (FP) and false-negative (FN) given by the infrared-AI software; thus, hit is the true positive (TP) and true negative (TN). N/A: information not available; -: bank cell; *: P value calculated by Fisher’s exact test
Thanks are due to FUCAM A.C. for facilitating communication with patients and for those little details given in this research, especially to the Department of Radiology.
The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: PASM, AHS, JAJA, LEHG, JAMG, and YGM report a relationship with Hearthcore SAPI de CV as associates, but declare to only have a scientific interest in this research. EMDCM reports a relationship with Hearthcore that includes non-financial support as a medical advisor. There are no further conflicts of interest to be declared.
Ethical approval
This research was conducted in accordance with the standards of the Research, Bioethics, and Biosafety Committee from FUCAM A.C. [PI 19-05], as well as with the 1964 Declaration of Helsinki and its later amendments.
Consent to participate
Informed consent to participate in the study was obtained from all participants.
Consent to publication
Informed consent to publication was obtained from relevant participants.
Availability of data and materials
The electronic patient record data used to support the findings of this research are restricted by FUCAM A.C. in order to protect patient’s privacy, also, the database of infrared images generated in this trial are property of Heathcore SAPI de CV. Requests for accessing the datasets should be directed to [Eva Ruvalcaba-Limon, evaruvalcaba@yahoo.com.mx] and [Pedro A. Sánchez-Méndez, pedro.sanchez@thermy.com.mx] if the researcher meets the criteria for access to confidential data.
Funding
This work was supported by the Social Responsibility Program of Avon Cosmetics S. de R.L. de C.V. [Cruzada Avon contra el Cáncer de Mama]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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