All ongoing oncology clinical trials involving the removal of soluble TNFR
Cytokine | Clinical trial ID | Phase | Number of patients | Cancer type | Treatment | Status | Estimated study completion date |
---|---|---|---|---|---|---|---|
TNFα | NCT04004910 | I/II | 170 | Advanced breast cancer | Three-way comparison between plasma soluble TNFR pulldown with or without chemotherapy, and chemotherapy alone | Recruiting | July 2023 |
TNFα | NCT04142931 | I | 30 | Stage IV non-small cell lung cancer, stage IV melanoma, triple-negative breast cancer, or stage IV renal cell carcinoma | Reduction of soluble TNFR, with or without nivolumab | Recruiting | December 2022 |
TNFα | NCT04690686 | II | 24 | Non-small cell lung cancer | Reduction of soluble TNFR alone, or with atezolizumab or paclitaxel | Recruiting | December 2022 |
EJ: Conceptualization, Methodology, Writing—original draft, Writing—review & editing.
The author declares that he has no conflicts of interest.
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© The Author(s) 2023.