Clinically approved HDAC IC50 values against all HDAC gene products [22]
| HDAC isozyme | Vorinostat, hydroxamate (nmol/L) | Tucidinostat, anilide (nmol/L) | Romidepsin, thiol (nmol/L) | Panobinostat, hydroxamate (nmol/L) | Belinostat, hydroxamate (nmol/L) |
| 1 | 60 | 100 | 1 | 3 | 26 |
| 2 | 42 | 200 | 1 | 2 | 22 |
| 3 | 36 | 100 | 1 | 2 | 19 |
| 4 | 20 | > 10,000 | 647 | 1 | 15 |
| 5 | 36 | > 10,000 | > 1,000 | 1 | 25 |
| 6 | 29 | > 10,000 | 226 | 1 | 10 |
| 7 | 129 | > 10,000 | > 1,000 | 2 | 51 |
| 8 | 173 | 700 | > 1,000 | 22 | 22 |
| 9 | 49 | > 10,000 | > 1,000 | 1 | 24 |
| 10 | 60 | 100 | 1 | 31 | 59 |
| 11 | 31 | 400 | 0.3 | 4 | 27 |
