Univariate analyses of potential viables for survival of patients with HCC

VariablesOSRFS
DR (95% CI)PtrendTRR (95% CI)Ptrend
Age (> 48 years old vs. 48 years old)a0.89 (0.70–1.12)0.310.88 (0.69–1.12)0.29
Gender (female vs. male)0.91 (0.71–1.17)0.470.90 (0.70–1.15)0.39
Ethnicity (Zhuang vs. Han)0.81 (0.64–1.02)0.070.77 (0.61–1.08)0.08
Smoking (yes vs. no)0.76 (0.58–0.99)0.050.76 (0.58–1.01)0.06
Drinking (yes vs. no)0.86 (0.66–1.12)0.260.82 (0.63–1.08)0.16
HBV status (positive vs. negative)1.04 (0.81–1.33)0.791.20 (0.93–1.55)0.16
HCV status (positive vs. negative)1.03 (0.72–1.48)0.861.03 (0.71–1.50)0.87
AFP (> 20 ng/mL vs. 20 ng/mL)1.11 (0.88–1.41)0.381.21 (0.95–1.55)0.13
Liver cirrhosis (yes vs. no)1.20 (0.92–1.58)0.191.13 (0.85–1.49)0.40
ES grade (high vs. low)1.48 (1.17–1.87)8.99 10–41.57 (1.24–1.99)2.11 × 10–4
MVD (positive vs. negative)1.39 (1.09–1.78)7.30 10–51.22 (0.96–1.57)0.11
Po-TACE treatment (yes vs. no)0.63 (0.50–0.80)9.80 10–50.61 (0.48–0.78)5.10 × 10–5
ADAs (high vs. low)b3.89 (2.95–5.12)4.66 10–223.08 (2.36–4.02)1.10 × 10–16

a Age is grouped according to the average age of patients with HCC (47.94 years old 9.98 years old); b ADAs are grouped according to the average ADA of patients with HCC (3.00 µmol/mol 1.51 µmol/mol DNA). Ptrend: P value is calculated by trend test in the models