Comparison of clinico-pathological features between patients with good and poor ALI
Parameter | Total | ALI | P-value | ||
---|---|---|---|---|---|
Good (> 28.02) | Poor (≤ 28.02) | ||||
BMI | < 18.5% | 285 | 9 | 47 | 0 |
18.5–24.99% | 59 | 102 | |||
25.0–29.99% | 34 | 27 | |||
≥ 30% | 6 | 1 | |||
Smoker | Yes | 285 | 22 | 37 | 0.91 |
No | 86 | 140 | |||
Age | ≤ 65 Years | 285 | 94 | 158 | 0.57 |
> 65 Years | 14 | 19 | |||
SMD | Good (> 36.62) | 285 | 42 | 58 | 0.29 |
Poor (≤ 36.62) | 66 | 119 | |||
Gender | Male | 285 | 55 | 104 | 0.20 |
Female | 53 | 73 | |||
Sarcopenia | Yes | 285 | 55 | 107 | 0.12 |
No | 53 | 70 | |||
mALI | Good (> 55.33) | 285 | 95 | 17 | 0 |
Poor (≤ 55.33) | 13 | 160 | |||
NLR | Good (≤ 3) | 285 | 94 | 16 | 0 |
Poor (> 3) | 14 | 161 | |||
Chemotherapy regimen received | Geftinib | 285 | 51 | 92 | 0.44 |
Pemetrexed plus platins | 57 | 85 | |||
Grades of drug toxicity | High grade | 273 | 61 | 109 | 0.62 |
Low grade | 40 | 63 | |||
Performance status | 0–1 | 285 | 103 | 165 | 0.46 |
≥ 2 | 5 | 12 | |||
Progression | Yes | 285 | 78 | 132 | 0.66 |
No | 30 | 45 | |||
Final status | Alive | 285 | 33 | 34 | 0.03 |
Dead | 75 | 143 |
Bold values indicate significant P-values
AM: Conceptualization, Project administration, Investigation, Methodology, Supervision, Validation, Writing—review & editing. DG: Conceptualization, Data curation, Formal analysis, Investigation, Writing—review & editing, Writing—original draft, Software. UA, KP, VN, AJ, NM, VP, and SS: Data curation, Investigation. All authors read and approved the submitted version.
The authors declare that they have no conflicts of interest.
The study was conducted after clearance from Institutional Ethics Committee (3088; Tata Memorial Hospital) and conducted in accordance with the guidelines of the Indian Council of Medical Research 2017. The research of this article meets the requirements of the Declaration of Helsinki.
Informed consent to participate in the study was obtained from all participants.
Informed consent to publication was obtained from relevant participants.
The datasets generated in this study are available on request to Abhishek Mahajan (drabhishek.mahajan@yahoo.in; abhiradiology@gmail.com).
Not applicable.
© The Author(s) 2023.