Main features of the studies included in the present systematic review
| Topic | Reference | Year | Country | N of patients | Topic |
|---|---|---|---|---|---|
| Surgical margins assessment | Costantino et al. [13] | 2023 | Italy | 453 | Prediction of positive surgical margins |
| Pertzborn et al. [14] | 2022 | Germany | 7 | Intraoperative assessment of tumour margins | |
| Tighe et al. [15] | 2021 | UK | 1,316 | Surgical margins after curative surgery | |
| Halicek et al. [16] | 2019 | USA | 102 | HSI for cancer margin detection | |
| Halicek et al. [17] | 2019 | USA | 12 | HSI for cancer detection | |
| Lu et al. [18] | 2017 | USA | 36 | HSI to detect cancers | |
| Fei et al. [19] | 2017 | USA | 16 | HSI for tumour margin assessment | |
| Complications assessment | Tighe et al. [20] | 2022 | UK | 1,593 | Free flap failure rates |
| Mascarella et al. [21] | 2022 | Canada | 43,701* | Major postoperative adverse events (MPAEs) | |
| Gan et al. [22] | 2022 | China | 632 | Risk factors for surgical site infection (SSI) | |
| Formeister et al. [23] | 2020 | USA | 364 | Complications in microvascular free tissue transfer | |
| Salvage surgery indication | Smith et al. [24] | 2020 | USA | 16,440 | Predicting salvage laryngectomy |
* Number of surgical interventions. N: number
