The characteristics of articles included in a systematic review of the effect of COVID-19 on HCC diagnosis

ReferencePlace (country)Sample sizeType of studyReview period or comparison dateQuality assessment
Vigliar et al. [23]Global (23 countries)41 Cytopathology laboratoriesInternational surveyThe same period in 2020 vs. 2019 (different for each country)Good
Amaddeo et al. [19]France

6 Referral centers (670):

2020: 293

2019: 377

Retrospective and cross-sectional studyFirst 6 weeks of the COVID-19 pandemic (exposed) vs. the same period in 2019 (non-exposed)Good
De Vincentiis et al. [16]ItalyGeneral hospitalShort report11th Through the 20th week of 2018 to 2020Good
Ferrara et al. [17]Italy7 Anatomic pathology units and secondary care hospital networksNAFrom weeks 11 to 20 of 2018, 2019, and 2020Good
Gandhi et al. [18]14 Asia-Pacific countries27 Hospitals: 2,789 and 2,045 patients with new HCC diagnoses during the pre-and pandemic periodSurveyFebruary to May 2019 vs. the same period in 2020Good
Grinspan et al. [24]New York1,028 Pathology samples from 949 patientsRetrospective cohort studyFebruary 1 to April 30, 2018 vs. same periods in 2019, 2020 and March 16, 2020 (as pre-COVID-19 and COVID-19 period in 2020)Good
Iavarone et al. [25] Italy

2019: 555

2020: 579

Retrospective study2020 vs. 2019Good
Kempf et al. [20]France

First time: 450 in 2018, 398 in 2019, and 303 in 2020

Second time: 513 in 2018, 522 in 2019, and 469 in 2020

ProspectivelyFrom January 1, 2018 to September 31, 2020 Good
Khan et al. [21]US41 HCOsRetrospective multicenter research network studyFrom March 15, 2020 to July 15, 2020, and March 15, 2019 to July 15, 2019Fair
Muñoz-Martínez et al [26]76 Countries76 Centres around the worldInternational surveyFrom May 2020 to June 2020Fair
Perisetti et al. [27]Global23,201 Patients hospitalized with alcohol-related hepatitisInternational surveyBetween January 1, 2020, and December 1, 2020) vs. the same period in 2019Good
Pomej et al. [22]Austria

104 Males

22 Females

RetrospectivelyBetween December 1, 2019 and June 30, 2020Good

HCOs: healthcare organizations; NA: not available