Patient and liver tumor characteristics prior to the start of treatment
Clinical variables | Value |
---|---|
Number of subjects | 48 |
Agea [mean ± standard deviation (SD), years] | 55.3 ± 18 |
Sex (female:male) | 25:23 |
Number of lesions | 94 |
KRAS positive | 29/48 (60.4%) |
Extrahepatic disease | 23/48 (47.9%) |
The median time between MRI and chemotherapy (days) | 23 |
Local tumor progression | 17/48 (35.4%) |
Chemoradiotherapy | 17/48 (35.4%) |
Follow-up (months) | 34.9 21 |
Location of primary tumor | |
Ascending colon | 35/48 (72.9%) |
Transverse colon | 2/48 (4.2%) |
Descending and sigmoid colon | 11/48 (22.9%) |
MSI | |
No testing available | 30/48 (62.5%) |
MSI-low (L) | 17/48 (35.4%) |
MSI-high (H) | 1/48 (2.1%) |
Tumor number | |
1 | 31/48 (64.6%) |
> 1 | 17/48 (35.4%) |
TNM classification | |
II or III | 4/48 (8.3%) |
IV | 44/48 (91.7%) |
Tumor size | |
≤ 3 cm | 61/94 (64.9%) |
> 3 cm | 33/94 (35.1%) |
Chemotherapy regimen | |
FOLFIRI | 4/48 (8.3%) |
FOLFOX | 44/48 (91.7%) |
a at the time of MRI
AT and DD: Conceptualization, Investigation, Validation, Writing—original draft, Writing—review & editing. BD and JN: Investigation, Writing—review & editing. MSG: Writing—review & editing, Supervision. All authors read and approved the submitted version.
The authors declare that they have no conflicts of interest.
This study was approved by the IRB of Massachusetts General Hospital [#2017P00004]. The research complies with the Declaration of Helsinki.
The consent to participate has been waived by the IRB of Massachusetts General Hospital given the retrospective nature of this study.
Not applicable.
The datasets for this manuscript are not publicly available because data contains personally identifiable information that may be restricted from public access to protect individuals’ privacy. Requests for accessing the datasets should be directed to (Azadeh Tabari, atabari@mgh.harvard.edu).
Not applicable.
© The Author(s) 2024.