Statistically significant radiomic features on univariate logistic regression and Wald test (P < 0.05)
| Parameters | Features | Coeff (95% CI) | P < 0.05 |
|---|---|---|---|
| First order | 10th Percentile | 0.78 (1.34, 0.19) | 0.01 |
| 90th Percentile | 0.80 (1.4, 0.2) | 0.01 | |
| Entropy | –1.82 (–0.22, –3.42) | 0.03 | |
| Maximum | 0.45 (0.87, 0.03) | 0.04 | |
| Mean | 0.95 (1.61, 0.3) | 0.01 | |
| Median | 0.88 (1.50, 0.26) | 0.01 | |
| Root mean squared | 1.10 (1.82, 0.38) | 0.01 | |
| Uniformity | 3.86 (7.37, 0.35) | 0.03 | |
| GLCM | Cluster prominence | –1.45 (–0.22, –2.69) | 0.02 |
| Cluster tendency | –2.06 (–0.09, –4.03) | 0.04 | |
| Contrast | –24.1 (–5.68, –42.5) | 0.01 | |
| Difference average | –24.1 (–5.68, –42.5) | 0.01 | |
| Difference entropy | –4.62 (–1.19, –8.06) | 0.01 | |
| Difference variance | –26.2 (–6.40, –45.9) | 0.01 | |
| Inverse difference (Id) | 48.1 (84.9, 11.4) | 0.01 | |
| Inverse difference moment (Idm) | 48.1 (84.9, 11.4) | 0.01 | |
| Inverse difference moment normalized (Idmn) | 120.3 (212.3, 28.4) | 0.01 | |
| Inverse difference normalized (Idn) | 72.2 (127.4, 17) | 0.01 | |
| Informational measure of correlation 2 (Imc2) | –1.92 (–0.27, –3.56) | 0.02 | |
| Inverse variance | –24.1 (–5.68, –42.5) | 0.01 | |
| Joint energy | 3.54 (6.57, 0.50) | 0.02 | |
| Joint entropy | –1.42 (–0.27, –2.57) | 0.02 | |
| Maximum probability | 4.54 (8.86, 0.22) | 0.04 | |
| Sum entropy | –1.50 (–0.27, –2.73) | 0.02 | |
| Sum squares | –7.86 (–0.73, –15) | 0.03 | |
| GLDM | Dep variance | –0.19 (–0.03, –0.35) | 0.02 |
| Gray level variance | –7.71 (–0.7, –14.7) | 0.03 | |
| Large dep emphasis | 0.03 (0.06, 0.01) | 0.01 | |
| Small dep emphasis | –1,509.4 (–468.9, –2,549.9) | 0.01 | |
| Small dep high gray level emphasis | –107.8 (–5.81, –209.7) | 0.04 | |
| GLRLM | Gray level non-uniform normalized | 3.36 (6.29, 0.44) | 0.02 |
| Gray level variance | –6.73 (–0.88, –12.6) | 0.02 | |
| Run percentage | –32.3 (–9.86, –54.8) | 0.01 | |
| Short run emphasis | –13.1 (–3.98, –22.3) | 0.01 | |
| Short run high gray level emphasis | –2.3 (–0.52, –4.07) | 0.01 | |
| GLSZM | Small area emphasis | –4.88 (–1.23, –8.48) | 0.01 |
| Small area high gray level emphasis | –4.15 (–1.21, –7.09) | 0.01 | |
| Small area low gray level emphasis | –4.33 (–0.49, –8.18) | 0.03 | |
| Zone entropy | –0.30 (–0.01, –0.59) | 0.05 | |
| Zone percentage | –1,362.4 (–174.1, –2,550.6) | 0.03 | |
| NGTDM | Complexity | –26.1 (–6.31, –45.9) | 0.01 |
| Contrast | –141.7 (–14.3, –269) | 0.03 |
