Expression of main GLUT isoforms related to OC
GLUT isoforms | Major site of expression | Nature of transport | References |
---|---|---|---|
GLUT1 | Placenta, brain, muscles, kidney, and colon | Basal continuous uptake | [26] |
GLUT2 | Liver, B-cell, kidney, and small intestine | Two-way transportation of glucose | [25] |
GLUT3 | Many tissues, including brain, placenta, and kidney | Neuronal uptake | [28] |
GLUT4 | Skeletal muscle, heart, and brown and white fat | Insulin-responsive | [29] |
FBA: Software, Formal analysis, Visualization, Investigation, Methodology, Writing—original draft, Writing—review & editing. ZQ: Writing—original draft, Writing—review & editing, Formal analysis, Funding acquisition, Supervision, Validation. MO: Formal analysis, Funding acquisition, Supervision, Validation, Writing—review & editing. ND: Supervision, Validation. YB: Supervision, Validation, Writing—original draft. ME: Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Writing—original draft, Writing—review & editing. RAEH: Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing—original draft, Writing—review & editing.
The authors declare that they have no conflicts of interest.
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This study was funded by the Moroccan Ministry of Higher Education, Scientific Research and Innovation and the OCP Foundation, APRD research program (APRD 2020). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
© The Author(s) 2024.