Table Info

Table 4.

Population, tumor, and treatment characteristics of the MBC cohort of ULS Santa Maria

Variable			Value
Demographic characteristic	Mean age (years)	-	39.4 (range 29–57)
Demographic characteristic	Gender (female)	-	100% (n = 5)
BRCA mutations (%, n patients)	BRCA1	-	20% (n = 1)
BRCA mutations (%, n patients)	BRCA2	-	80% (n = 4)
Tumor characteristic (%, n patients)	Histologic subtype	NST	100% (n = 5)
	Molecular subtype	Luminal B HER2-negative	80% (n = 4)
	Molecular subtype	TNBC	20% (n = 1)
	Differentiation grade	2	60% (n = 3)
	Differentiation grade	3	40% (n = 2)
	Stage	II	40% (n = 2)
	Stage	IV	60% (n = 3)
	PARPi [80% (n = 4)]	Olaparib	20% (n = 1)
	PARPi [80% (n = 4)]	Talazoparib	60% (n = 3)
	Platinum	-	30% (n = 2)
Line of treatment (PARPi therapy; %, n patients)	Second line	-	40% (n = 2)
	Third line	-	20% (n = 1)
	Fourth line	-	20% (n = 1)

HER2: human epidermal growth factor receptor 2; NST: no special type; PARPi: poly[adenosine diphosphate (ADP)-ribose] polymerase inhibitor; TNBC: triple negative breast cancer; BRCA: BReast CAncer gene; HER2: human epidermal growth factor receptor 2; -: no data

Declarations

Author contributions

VP and SC: Conceptualization, Investigation, Writing—original draft, Writing—review & editing. CA: Visualization, Conceptualization, Writing—review & editing. TB: Data curation, Writing—review & editing. RTdS: Conceptualization, Writing—review & editing. ST, LAR, GNC, HLP, CP, and Leila C: Writing—review & editing. Luís C: Visualization, Conceptualization, Writing—review & editing.

Conflicts of interest

The authors declare no conflicts of interest.

Ethical approval

This study was approved by the ethics committee of COMISSÃO DE ÉTICA DO CAML.

Consent to participate

The consent to participate has been waived by the IRB of COMISSÃO DE ÉTICA DO CAML given the retrospective nature of this study.

Consent to publication

Not applicable.

Availability of data and materials

The raw data supporting the conclusions of this manuscript will be made available by the authors (Vanessa Patel, vanessacpatel@gmail.com) , without undue reservation, to any qualified researcher.

Funding

Not applicable.

Copyright

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