Database search engines and algorithms in database search engines used for identification of MHC binding peptides (pMHC) and post-translational modification (PTM) of identified peptides

Search enginesDB searchDe novo peptide sequencingPTM search*
Proteome DiscovererSEQUESTINFERY™ProsightPD
MaxquantAndromedaMaxNovoAndromeda
PEAKSPEAKSPEAKS BDGlycanFinder
MSFraggerMSFraggern/aMSFragger-glyco
MetaMorpheusMetaMorpheusn/aG-PTM-D
PepNoVo+n/aPepNOVO+n/a
SMSnetSMSnetSMSnetSMSnet

* Database search for PTM can be phosphorylation, glycosylation, or other type of PTM