LncRNAs associated with DNMTs silencing genes by CpG methylation
lncRNA | recruitment | target | Mechanism | Reference |
---|---|---|---|---|
ecCEBPA | DNMT1 | CEBPA | - | [92] |
DACOR | DNMT1 | DNMT1 | Decoy | [93, 94] |
LINC0051 | EZH2 | PTEN | CpG methylation | [95] |
HOTAIR | DNMT1 | PTEN | CpG methylation | [96] |
SAMD12-AS1 | DNMT1 | P53 | CpG | [97] |
KIF9-AS1 | DNMT1 | RAI2 | CpG | [98] |
HOTAIR | DNMT1 | miR-122 | CpG | [99] |
TINCR | DNMT1 | miR-503 | CpG | [100] |
AIRN | Steric hindrance | IGFR2R | CpG | [101, 102] |
HITT | EZH2, PRC2 | Hif-1alpha | Triplex formation | [85] |
CDKN2B-AS1 | PRC2 | CDKN2B | Triplex formation | [84] |
ecCEBPA: Extra-coding CEBPA; HOTAIR: HOX transcript antisense intergenic RNA; PTEN: phosphatase and tensin homolog; PRC1: Polycomb repressive complexes 1; -: blank cell
PP: Writing—review and editing.
The author declares that he has no conflicts of interest.
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© The Author(s) 2024.