Table Info

Table 2.

General characteristics of studies on the role of NLR in tCa diagnosis

Reference	Sample size	Study design	Year of publication	Country	Histopathology	Cut off value of NLR	Seminomatous tCa	Outcome
Arıman and Merder [27]	152	Retrospective cohort	2021	Turkey	tCa	2.39	52.60%	NLR in healthy control group patients was significantly lower than patients with tCa.
Arda et al. [26]	182	Retrospective cohort	2020	Turkey	TGCT	1.78	46.60%	B-HCG level was significantly higher in the patients with higher NLR.
Başer and Aras [28]	83	Retrospective cohort	2020	Turkey	TGCT	2.27	60.00%	NLR values of the tCa patients were significantly higher than healthy controls.
Çalışkan et al. [30]	285	Retrospective cohort	2017	Turkey	tCa	1.64	37.00%	The NLR level was significantly higher in tCa group than those with benign pathology.
Kopru et al. [42]	80	Retrospective cohort	2019	Turkey	tCa	-	51.51%	Patients with tCa had a higher NLR compared to the control group with benign pathology.
Selvi and Başar [49]	96	Retrospective cohort	2020	Turkey	tCa	-	50.00%	NLR was significantly higher in patients with tCa than those with benign testis masses.
Girgin et al. [32]	76	Retrospective cohort	2021	Turkey	tCa	2.06	34.21%	The NLR values in patients with tCa were significantly higher than those with varicocele.
Gokcen et al. [33]	121	Retrospective cohort	2018	Turkey	TGCT	2.25	-	NLR was significantly higher in patients with tCa than those with varicocele.
Kartal et al. [40]	160	Retrospective cohort	2020	Turkey	TGCT	2.25	43.58%	NLR was significantly higher in patients with tCa than in the varicocele patients.
Şahin et al. [47]	291	Cross-sectional retrospective	2019	Turkey	tCa	3.16	-	NLR was significantly higher in patients with testicular tumor than in those with varicocele.
Yuksel et al. [54]	72	Retrospective cohort	2016	Turkey	tCa	2.06	16.66%	NLR was statistically higher in patients with tCa compared with varicocele patients.

tCa: testicular cancer; TGCT: testicular germ cell tumor; NLR: neutrophil to lymphocyte ratio

Declarations

Author contributions

SS: Conceptualization. SB: Investigation, Writing—original draft. SK: Conceptualization, Writing—review & editing. AS: Investigation. AC: Investigation. DK: Writing—original draft. MK: Writing—review & editing. AG: Writing—review & editing. BLW: Writing—review & editing.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Datasets are available on request.

Funding

Not applicable.

Copyright

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