General characteristics of studies on the role of NLR in differentiating between different types of tCa

ReferenceSample sizeStudy designYear of publicationCountryHistopathologyCut off value of NLRSeminomatous tCaOutcome
Arıman and Merder [27]152Retrospective cohort2021TurkeytCa2.3952.60%There was no statistically significant difference between cases with seminoma and non-seminomatous tCa.
Jankovich et al. [38]103Retrospective cohort2017SlovakiaTGCT439.80%There was no statistically significant difference in NLR level between patients with seminomas and non-seminomatous tCa.
Kopru et al. [42]80Retrospective cohort2019TurkeytCa-51.51%No statistically significant difference, was found in NLR of patients with seminomas and non-seminomatous tCa groups.
Köşeci et al. [43]72Retrospective cohort2021TurkeyTGCT2.543.00%NLR level wasn’t significantly different between seminomas and non-seminomatous tCa groups.
Olcucu et al. [44]99Retrospective cohort2020TurkeyTGCT3.2145.45%There was no significant correlation between NLR and different types of tCa.
Horsanali et al. [36]128Retrospective cohort2017TurkeyTGCT3.7244.80%There was statistically significant difference in NLR between different tumor histopathology.

tCa: testicular cancer; TGCT: testicular germ cell tumor; NLR: neutrophil to lymphocyte ratio