General characteristics of studies on the association of NLR with tumor size in tCa

ReferenceSample sizeStudy designYear of publicationCountryHisto
pathology
Cut off value of NLRSeminomatous tCaOutcome
Hamidi et al. [34]72Retrospective cohort2018TurkeytCa2.3930.50%NLR was significantly associated with tumor size of the tCa patients.
Ilktac et al. [37]61Retrospective cohort2020TurkeyTGCT2.5659.00%A significant correlation between tumor size and NLR was reported.
Olcucu et al. [44]99Retrospective cohort2020TurkeyTGCT3.2145.45%NLR was significantly related to tumor size.
Kopru et al. [42]80Retrospective cohort2019TurkeytCa-51.51%No statistically significant relationship was observed between testicular tumor size and NLR.
Köşeci et al. [43]72Retrospective cohort2021TurkeyTGCT2.543.00%NLR was not significantly associated with tumor size.
Tan et al. [2]160Retrospective cohort2019SingaporetCa363.80%No difference in the tumor size between patients with different NLR values was observed.

tCa: testicular cancer; TGCT: testicular germ cell tumor; NLR: neutrophil to lymphocyte ratio