General characteristics of studies on the association of NLR with conventional tumor markers of tCa

ReferenceSample sizeStudy designYear of publicationCountryHisto
pathology
Cut off value of NLRSeminomatous tCaOutcome
Arda et al. [26]182Retrospective cohort2020TurkeyTGCT1.7846.60%B-HCG level was significantly higher in the patients with higher NLR.
Horsanali et al. [36]128Retrospective cohort2017TurkeyTGCT3.7244.80%Levels of AFP, B-HCG, and LDH were significantly related to NLR level.
Olcucu et al. [44]99Retrospective cohort2020TurkeyTGCT3.2145.45%NLR was significantly related to LDH level.
Bauzá Quetglas et al. [46]80Retrospective cohort2020SpaintCa2.2562.50%No correlation was observed between NLR and conventional tumor markers (AFP and B-HCG).

tCa: testicular cancer; TGCT: testicular germ cell tumor; NLR: neutrophil to lymphocyte ratio