Colorectal cancer cell lines with or without APC and other WNT/β-catenin pathway mutations

Cell lineDepMap IDTMBFGAPloidyMSI status
Quadruple mutated
CL-34ACH-00089542.733330.1491.98NA
CW-2ACH-000998274.96670.02932MSI
GP2dACH-000982169.20.04182NA
HCT-15ACH-000997259.66670.02692MSI
KM12ACH-000969110.70.13042MSI
LoVoACH-00095077.50.20922.2MSI
LS411NACH-000985182.06670.28073.41MSI
NCI-H630ACH-00228775.4NANANA
SNU-C2AACH-000967104.16670.10341.98NA
SNU-C4ACH-00095973.466670.03371.99NA
SNU-C5ACH-000970100.03330.09662.05MSI
APC only mutated
C75ACH-0014588.333333NANANA
C80ACH-0014597.133333NANANA
C84ACH-0014607.566667NANANA
CACO2ACH-0000035.6NANANA
COLO 201ACH-0002538.8666670.382.96MSS
DiFiACH-0022337.2NANAMSS
GEOACH-00239411.13333NANAMSS
HCC2998ACH-001081233.4333NANAMSS
MDST8ACH-00093525.866670.55832.12MSS
SK-CO-1ACH-0004009.90.5523.68MSS
SNU-175ACH-000989183.86670.09272.05MSI
SW1116ACH-00048912.033330.63392.76MSS
SW1417ACH-0002368.50.56833.12MSS
Triple mutated
HCC-56ACH-00046712.966670.52882.94NA
HCT 116ACH-000971106.50.0822.06MSI
LIM1215ACH-00154630.36667NA1.97MSI
LS1034ACH-00025212.40.35623.11MSS
NCI-H508ACH-00036010.733330.48132.31MSS
NCI-H716ACH-00049114.10.61372.83MSS
RKOACH-000943114.66670.14212.15MSI
SNU-407ACH-00095588.333330.08952.08MSI
SNU-C2BACH-00119986.2NA2.02MSI
Quadruple wild type
C10ACH-0014547.233333NANANA
C99ACH-0014616.9NANANA
CAR1ACH-0023457.833333NA2.77MSS
LS513ACH-00000713.90.26362.28MSS

TMB: tumor mutation burden; FGA: fraction genome altered; MSI: microsatellite instability; MSS: microsatellite stability; NA: not available; APC: adenomatous polyposis coli. Data are from the Cancer Cell Line Encyclopedia (CCLE)