CTCs properties and related markers associated with EMT program in lung cancer
CTCs properties | Biomarkers | Ref. |
---|---|---|
Epithelial | EpCAM, E-cadherin, CK7, CK8, CK18, CK19 | [20, 21] |
Mesenchymal | Vimentin, N-cadherin, | [21, 22] |
EMT | EpCAMLow, E-cadherinLow, CKLow, VimentinHigh, N-cadherinHigh, Twist | [21, 22] |
Stem-like | CD44, CD133, ALDH1 | [17, 22, 23] |
EpCAM: epithelial cell adhesion molecule; CK: cytokeratin; ALDH1: aldehyde dehydrogenase 1
SDV: conception and design of the manuscript, writing of the manuscript, revision of the final version of the manuscript; VD and RF: writing of the manuscript, revision of the final version of the manuscript; FI: conception and design of the manuscript, writing of the manuscript, revision of the final version of the manuscript.
The authors declare that they have no conflicts of interest.
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Informed consent to participate in the present manuscript was obtained from all participants.
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© The Author(s) 2021.