Table Info

Table 3.

Vitamin D and response to vaccination

Condition	Age/years old	Study	Results	Reference
Healthy, community-dwelling individuals	≥ 65	Influenza vaccination H1N1, H3N2, or B virus	Levels of Vitamin D were not correlated with seroprotection or seroconversion	[72]
Healthy individuals	50–74	Influenza vaccination A/California/H1N1-like virus	Vitamin D levels at baseline correlated with day 28 hemagglutination inhibition assay	[73]
Healthy individuals	18–49	1 mg 1,25OH at the site adjacent to influenza vaccine	Hemagglutination inhibition assay (H1N1, H3N2, B virus) is not different in comparison with placebo	[82]
Healthy individuals	26–35	2,000 IU vitamin D/day for 9 weeks, vaccination tetanus/ diphtheria toxoid	Discrete higher IgG levels and no difference in specific IgA in comparison with placebo	[83]
Splenectomised patients	≥ 40	Vaccinated against S. pneumoniae or Neisseria meningitides	Same levels of vitamin D at baseline, similar production of antibodies	[81]

Declarations

Author contributions

VB: Writing—original draft, Writing—review & editing.

Conflicts of interest

The author declares that there are no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

The study was supported by CAPES PrInt UNIFESP [88881.310735/2018-01]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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