Vitamin D and COVID-19

ConditionAge/years oldStudyResultsReference
COVID-19 and vitamin D levels

65 ± 13

70 ± 14

Levels of vitamin D 12 ng/mL or 8 ng/mLSurvivors presented higher levels of vitamin D than non-survivors[87]
COVID-19 and vitamin D levelsMedian 63Levels of vitamin D 17 ng/mL to 33 ng/mL No correlation between prehospitalization vitamin D and clinical outcomes[91]
COVID-19, vitamin D supplement

66 ± 11

65 ± 11

200,000 IU vitamin D intramuscularly

1 mcg/day vitamin D orally

Reduced incidence of mechanical ventilation, ICU, death, sepsis and atrial fibrillation in higher dose intramuscularly[92]
COVID-19, vitamin D supplement59 ± 10High single oral dose 500,000 IU x placeboNo prevention in the respiratory worsening and no significant effects on the length of hospital stay[93]
COVID-19, vitamin D supplement56 ± 14High single oral dose 200,000 IU x placeboSimilar length of hospital stays, in-hospital mortality, ICU, mechanical ventilation[94]
COVID-19, vitamin D, and vaccination53–69800 IU/day or 3,200 IU/day x placeboNo difference on breakthrough SARS-CoV-2 infection, post-vaccination titers of anti-S or neutralizing antibodies[95]
COVID-19, vitamin D, and vaccination40 ± 11Vitamin D levels higher than 50 nmol/LHigher levels of anti-S post-vaccine[96]