Table Info

Table 5.

Pearson’s correlation coefficients (|r| > 0.3) between the TRP-KYN pathway metabolites and cytokine levels (A) and between PASI score and cytokine levels (B) in PSOs

(A)	TRP-KYN pathway metabolites	Cytokines	Correlation coefficient
	AA	IP-10	0.64
	KYN	IP-10	0.49
	AA	FLT3-L	0.38
	TRP	EGF	0.37
	KYN	MIG	0.37
	AA	MDC	0.32
	AA	MIG	0.32
	TRP	MIG	–0.32
	AA	MIP-1β	0.31
	3HK	IL-17F	–0.31
	KYNA	IP-10	0.30
	AA	Fractalkine	0.30
	KYN	FLT3-L	0.30
(B)	PASI score	Cytokines	Correlation coefficient
	PASI score	IL-1RA	0.45
	PASI score	IL-9	–0.30

Declarations

Acknowledgments

The authors would like to thank Mrs. Kayoko Tanaka for assisting data collection.

Author contributions

Seishima M and KS contributed conception and design of the study; RS and YY performed the experiments; KF and YM organized the database; Sakurai M and YY performed the statistical analysis; Seishima M wrote the first draft of the manuscript. All authors contributed to manuscript revision, read and approved the submitted version.

Conflicts of interest

The authors declare that there are no conflicts of interest.

Ethical approval

The study protocol was approved by the ethics committee of Gifu University Graduate School of Medicine (2018–1949).

Consent to participate

The informed consent to participate in the study was obtained from all participants.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

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