Genotypic results of IL-6 (-174G/C) polymorphism in the literature

GenotypeControlsHT patients
IL-6 -174 G>CGGGCCCGGGCCC
Our study (West Algeria)166/211
(78.67%)
43/211
(20.38%)
02/211
(0.95%)
65/81
(80.25%)
16/81
(19.75%)
0
Erdogan et al. [16] (Turkey)5/110
(4.5%)
86/110
(78.2%)
19/110
(17.3%)
27/110
(24.5%*)
51/110
(46.4%*)
32/110
(29.1%*)
Baki et al. [17] (Turkey)126/231
(54.6%)
90/231
(39%)
15/231
(6.5%)
117/190
(61.6%)
63/190
(33.2%)
10/190
(5.2%)
Durães et al. [18] (Portugal)319/735
(43.4%)
324/735
(44.1%)
92/735
(12.5%)
156/418
(37.3%)
189/418
(45.2%)
73/418
(17.5%*)
Aberkan [19] (Blida, center of Algeria)26/35
(74.29)
8/35
(22.86)
1/35
(2.86)
21/27
(80.77)
1/27
(3.70)
5/27
(18.52)

* Results statistically significant (P value < 0.05). HT: Hashimoto’s thyroiditis; IL-6: interleukin-6