NAbs titer and vitamin D concentration based on individual characteristics
Variables
NAb (IU/mL)
Vitamin D (ng/mL)
Mean
Range
P
Mean
Range
P
Age
≤ 60 yrs
35.24 ± 24.65
0.50–95.58
0.013a
12.76 ± 6.12
3.40–30.90
0.026b
> 60 yrs
42.92 ± 30.26
0.50–91.77
19.02 ± 9.27
7.60–41.20
Gender
Male
32.89 ± 23.11
0.50–95.58
0.289b
13.08 ± 3.85
5.10–19.90
0.231b
Female
42.67 ± 29.23
0.50–91.77
16.14 ± 10.31
3.40–41.20
BMI (kg/m2)
Non-obese
43.64 ± 27.70
0.50–91.77
0.004a
15.18 ± 8.21
5.10–41.20
0.487b
Obese
22.29 ± 17.70
0.50–61.32
12.77 ± 5.72
3.40–24.70
Comorbid
(–)
44.40 ± 27.30
0.50–95.58
0.034a
13.35 ± 6.82
5.10–32.80
0.210b
(+)
27.13 ± 23.18
0.50–78.19
16.08 ± 8.44
3.40–41.20
Ratio CD4/CD8*
≥ 1.0
40.55 ± 25.85
0.50–95.58
0.223a
14.60 ± 7.16
5.10–32.80
0.777b
< 1.0
29.65 ± 26.52
0.50–91.77
14.15 ± 8.68
3.40–41.20
a Independent t-test; b Mann-Whitney test; * The CD4/CD8 ratio in healthy individuals between 1.0 and 4.0 is generally considered normal. NAbs: neutralizing antibodies
Declarations
Acknowledgments
We thank Prodia Clinical Laboratory for examining the blood samples.
Author contributions
HR: Conceptualization, Investigation, Data curation, Formal analysis, Methodology, Writing—original draft. FT, GP, and AAP: Writing—review & editing. SF: Data curation, Writing—review & editing. All authors read and approved the submitted version.
Conflicts of interest
The authors declare that they have no conflicts of interest.
Ethical approval
The studies involving human participants were reviewed and approved by the Ethics Committee of Immanuel Hospital, Bandung, Indonesia (ethics approval number: 36/A01/EC/IX/2021).
Consent to participate
Informed consent to participate in the study was obtained from all participants.
Consent to publication
Not applicable.
Availability of data and materials
The data presented in this study are available on request from the corresponding author.
Funding
This study was supported by the Universitas Kristen Maranatha, Bandung, Indonesia, under the B scheme. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.
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