Table Info

Table 6.

Epidemiological risk factors in PE and miscarriage

	PE	Miscarriage
Inadequate induction of tolerance
First pregnancy	○	×
The second pregnancy reduces the risk, even if the first pregnancy is a miscarriage	○	×
First pregnancy with a new partner in multiparous women	○	×
More than 10 years after the last delivery, the risk increases even if adjusted by age	○	×
IVF-ET	○	×
Low or lack of semen exposure
Condom use	○	×
Short cohabitation	○	×
Sperm donation pregnancy	○	×
Egg donation pregnancy	○	○
Embryo donation pregnancy	○	○
Fetus is a complete allograft to maternal host
Egg donation pregnancy	○	○
Embryo donation pregnancy	○	○
Hydatidiform mole	○	○

○:

risk factor; ×: not risk factor

Declarations

Author contributions

SS wrote the paper, and AN consulted on the content of the paper. TS did research on Treg and consulted on the content of the paper. ST submitted materials for the paper.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

This study was supported by Japan Agency for Medical Research and Development (grant JP18gk0110018 and JP21gk0110047) and Japan Society for the Promotion of Science (KAKENHI grant JP19K09750, 20K09614, 19K18690 and 21K16764). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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