Most common γδ T cell subsets in mouse and human

Circulating subsetsTissue-resident subsets
MouseVγ1.1+
Vγ2+
Vγ3+ (epidermis)
Vγ4+ (dermis, lung, uterus, adipose, liver)
Vγ5+ (gut)
HumanVδ2+Vδ1+ (epidermis, dermis, adipose, gut, liver)

Note. Adapted from “γδ T cells in cancer [12]” by Silva-Santos B, Serre K, Norell H. Nat Rev Immunol. 2015;15:683–91 (https://pubmed.ncbi.nlm.nih.gov/26449179/). © 2015 Macmillan Publishers Limited.