Adipokines and observations in PCOS
Adipokine | Action | Serum levels in PCOS | References |
---|---|---|---|
Adiponectin | Insulin sensitivity, inflammatory reaction, ovarian folliculogenesis | Decreased in PCOS | [164, 165, 167, 168] |
Visfatin | Insulin mimetic action | Increased in PCOS | [169–171] |
Resistin | Resist insulin action | Increased/unchanged in PCOS | [172–174] |
Leptin | Regulatory role in body mass, food intake, reproductive function, pro-inflammatory immune reaction, and lipolysis | Increased/unchanged in PCOS | [176, 195] |
Vaspin | Insulin sensitivity | Increased/decreased/unchanged in PCOS | [177–181] |
ML contributed conception and design of the study, reviewing and editing; BSJ wrote the first draft of the manuscript and analyzed the literature. All authors contributed to manuscript revision, read and approved the submitted version.
The authors declare that they have no conflicts of interest.
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ML is supported by Department of Biotechnology (DBT)-Rajiv Gandhi Centre for Biotechnology. BSJ is supported by a Senior Research Fellowship from ICMR [RBMH/FW/2020/2]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
© The Author(s) 2022.