Table Info

Table 3.

CAR-γδ T cell-based immunotherapy research

Target	Endodomain	Tumor type	Reference
GD2	TCRξ	Neuroblastoma	[100]
GD2	CD28-CD3ξ	Neuroblastoma/Ewing’s sarcoma	[95]
GD2	DAP10/CD28-CD3ξ	Neuroblastoma/Ewing’s sarcoma	[102]
CD19	Non	T-ALL	[103]
CD19	CD28-CD3ξ	B cell lymphoma/CLL	[99, 101]
CD19	TCRξ	B cell lymphoma/CLL	[100]
MCSP	CD28-CD3ξ	Melanoma	[96]
CD5	Non	B cell lymphoma/CLL	[103]

MCSP: melanoma-associated-chondroitin-sulfate-proteoglycan

Declarations

Author contributions

JZ and XJ wrote the initial draft of the manuscript; JZ prepared the figure; HZ and WW organized literature for manuscript; XW and ZJ revised the final draft. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

This study was supported in part by grants from the National Natural Science Foundation of China (Nos. 81800143, 81770150, 81200388, and 82170220), Natural Science Foundation of Guangdong Province (No. 2020A1515010817 and 2022A1515010313), the Science and Technology Program of Guangzhou City (No. 202201010164), National Innovation and Entrepreneurship Training Program for Undergraduate (No. 202010559081), Guangdong’s Innovation and Entrepreneurship Training Program for Undergraduate (Nos. 202010559081 and 202210559083), “Challenge Cup” National Undergraduate curricular academic science and technology works by race (No. 21112027) and Guangdong College Students’ Scientific and Technological Innovation (Nos. CX22438, CX22446, and CX21285). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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