List of nanomedicine for cancer therapy
| NPs | Synthesis methods | Cancer type | Route of administration | Drug utilized | Important result | References |
|---|---|---|---|---|---|---|
| Liposomes | Liposomes can be synthesized by various methods such as film hydration method, ether injection method, and sonication method. | Breast cancer | Intravenous | Paclitaxel | Enhances the delivery of drugs to tumor sites and reduces toxicity to healthy cells. | [83, 84] |
| Polymeric NPs | Polymeric NPs can be synthesized by various methods such as nanoprecipitation, solvent evaporation, and emulsion-diffusion methods. | Non-small cell lung carcinoma | Oral | Cisplatin | Enhances the delivery of drugs to the tumor sites and improves targeted therapy | [85] |
| Dendrimers | Dendrimers can be synthesized by divergent and convergent methods. | Prostate cancer | Topical | Docetaxel | Enhances the delivery of drugs to cancer cells and improve targeted therapy | [86, 87] |
| Gold NPs | Gold NPs can be synthesized by methods such as seed-mediated growth, reduction of HAuCl4 and citrate reduction. | Melanoma | Intravenous | Dox | Induces apoptosis in cancer cells and enhances the efficacy of chemotherapeutic drug | [88, 89] |
| Silica NPs (SNPs) | SNP can be synthesized by sol-gel, Stober method, and reverse micelle method. | Pancreatic cancer | Oral | Gemcitabine | Enhances the efficacy with no evidence of local or systemic toxicity | [90, 91] |
