Table Info

Table 1.

The immunologic biomarkers of MG

Auto-antibodies	Immune cells and cytokines	Molecules
AChR antibodies	Th1/17	PD-1/PD-L1 suppression
LRP4 antibodies	Tfr/Tfh ratio	ICOS/ICOSL activation
MuSK antibodies	CD4⁺CXCR5⁺FOXP3⁺ Tfr-like	Metalloproteinase 10
FLC of autoantibodies	CD4⁺CXCR5⁺FOXP3⁻ Tfh-like	TGFα
Collagen Q antibodies	GM-CSF-expressing Th	S100A12
Collagen XIII antibodies	TNF-producing Th CD103	C-C motif ligand 19
Acetylcholinesterase antibodies	IL-17A, IL-21, IL-10, IL-14, IL-2, IL-5, IL-12, IL-P70, IL-33, IL-6, IL-8, IL-19, IL-20, IL-28A, IL-35, IL-27, IL-36γ	C-X-C motif ligand 1
Rapsyn antibodies	IFN-γ	ICAM-1
Cortactin antibodies	-	CD25 and CD72
Titin antibodies	-	Tim-1
Kv1.4 antibodies	-	-
Agrin antibodies	-	-
RyR antibodies	-	-

-: blank cells

Declarations

Author contributions

FA: Conceptualization, Writing—immunologic, gut microbiome, and other biomarkers section. RR: Conceptualization, Writing—genetic factors and miRNA biomarkers section. Both of the authors contributed to manuscript revision, read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

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