miRNA markers for MG diagnosis
EOMG | TAMG | MuSK+ MG | AChR+ MG | LOMG |
---|---|---|---|---|
Down-regulation:miR-7-5p, miR-29, miR-548k, miR-145, miR-24, and miR-143, miR-146 | Up-regulation:let-7a-5p, let-7f-5p, miR-125a-5p | Down-regulation:miR-210-3p, miR-324-3p | Down-regulation:miR-15b, miR-122, miR-140-3p, miR-185, miR-192, miR-20b, and miR-885-5p, miR-27a-3p | Up-regulation:miR-30e-5p, miR-150-5p, miR-21-5p, miR-106b-3p, miR-223-5p, miR-140-5p, miR-19b-3p |
Up-regulation:miR-150-5p, miR-21-5p | Up-regulation:let-7a-5p, let-7f-5p, miR-125a-5p | Up-regulation:miR-151a-3p, let-7f-5p, let-7a-5p, miR-423-5p | Up-regulation:miR-150-5p and miR-21-5p | - |
Up-regulation in PBMCs:miR-612, miR-3654, miR-3651, and precursor miR-3651 | - | - | - | - |
PMBC: peripheral blood mononuclear blood cell; -: blank cells
FA: Conceptualization, Writing—immunologic, gut microbiome, and other biomarkers section. RR: Conceptualization, Writing—genetic factors and miRNA biomarkers section. Both of the authors contributed to manuscript revision, read and approved the submitted version.
The authors declare that they have no conflicts of interest.
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© The Author(s) 2022.